Intervertebral disc degeneration is a common cause of discogenic low back pain resulting in
significant disability. Current conservative or surgical intervention treatments do not reverse …

Intervertebral disc degeneration (IDD) is a common degenerative musculoskeletal disorder
and is recognized as a major contributor to discogenic lower back pain. However, the …

Although degeneration of the nucleus pulposus (NP) is a major contributor to intervertebral
disc degeneration (IVDD) and low back pain, the underlying molecular complexity and …

Circadian clock disorder during tissue degeneration has been considered the potential
pathogenesis for various chronic diseases, such as intervertebral disc degeneration (IVDD) …

As a controllable biological process, regulated cell death (RCD) extensively participates in
cellular homeostasis, organismal development, and the pathogenesis of diseases. This …

Intervertebral disc degeneration is thought to be a major contributor to low back pain, the
etiology of which is complex and not yet fully understood. To compensate for the lack of drug …

This study aimed to investigate the causal risk factors for intervertebral disc disorders (IVDD)
to help establish prevention strategies for IVDD‐related diseases. We performed two …

As the leading cause of disability worldwide, low back pain (LBP) is recognized as a pivotal
socioeconomic challenge to the aging population and is largely attributed to intervertebral …

This systematic review aims to find effectful healthcare strategies, with special focus on drug-
free interventions and physical therapy, as part of the treatment for sleep in patients with …

Intervertebral discs (IVDs) are rhythmic tissues that experience daily low‐load recovery.
Notably, aging and abnormal mechanical stress predispose IVDs to degeneration due to …