Strategies for surface modification of gelatin-based nanoparticles

MM Saber - Colloids and Surfaces B: Biointerfaces, 2019 - Elsevier
Recently developed methodologies related to surface modification of nanoparticles provide
nano systems with the final properties required for a desired application. In nano …

Nanobiomaterials in support of drug delivery related issues

X Joseph, V Akhil, A Arathi, PV Mohanan - Materials Science and …, 2022 - Elsevier
Nanobiomaterials have been widely accepted as potential drug delivery agents over the
past decade. A wide variety of materials have been utilized as drug delivery carriers for …

Microfluidic formulation of curcumin-loaded multiresponsive gelatin nanoparticles for anticancer therapy

Y Xia, R Xu, S Ye, J Yan, P Kumar… - … Science & Engineering, 2023 - ACS Publications
Current anticancer research shows that a combination of multiple treatment methods can
greatly improve the killing of tumor cells. Using the latest microfluidic swirl mixer technology …

The Effect of Okra (Abelmoschus esculentus (L.) Moench) Seed Extract on Human Cancer Cell Lines Delivered in Its Native Form and Loaded in Polymeric Micelles

W Chaemsawang, W Prasongchean… - International Journal …, 2019 - Wiley Online Library
Cancer is a noncommunicable disease with a high worldwide incidence and mortality rate.
The National Cancer Institute of Thailand reports increasing cumulative incidence of breast …

Hybrid nanoarchitecture of gelatin-modified silica-chitosan as an efficient delivery platform and functional role of crosslinking

Z Niazi, M Ashjari - International Journal of Polymeric Materials and …, 2024 - Taylor & Francis
A novel hybrid of a quercetin-loaded silica-chitosan, modified by crosslinked gelatin-folate
was developed in the current study as a pH-sensitive drug delivery system. The entrapment …

[HTML][HTML] Innovative gelatin-based micelles with AS1411 aptamer targeting and reduction responsiveness for doxorubicin delivery in tumor therapy

J Yu, Y Zhang, M Xu, D Jiang, W Liu, H Jin… - Biomedicine & …, 2024 - Elsevier
Herein, we constructed innovative reduction-sensitive and targeted gelatin-based micelles
for doxorubicin (DOX) delivery in tumor therapy. AS1411 aptamer-modified gelatin-ss …

Development and Characterization of Quercetin-Loaded Polymeric Liposomes with Gelatin–Poly (ethylene glycol)–Folic Acid Coating to Increase Their Long …

AM Nguyen-Huu, NTT Le, MH Vo Do… - ACS Applied Bio …, 2024 - ACS Publications
Liposomes as drug-delivery systems have been researched and applied in multiple
scientific reports and introduced as patented products with interesting therapeutic properties …

Folate-mediated targeting of carrageenan-cholesterol micelles for enhanced breast cancer treatment

F Shabani, R Karimi-Soflou, A Karkhaneh - European Polymer Journal, 2024 - Elsevier
A major cause of cancer-related mortality worldwide is metastatic breast cancer. Effective
treatment relies on the targeted penetration of tumors and the controlled drug delivery. Here …

Preparation of folate and carboxymethyl-β-cyclodextrin grafted trimethyl chitosan nanoparticles as co-carrier of doxorubicin and siRNA

Y Zhang, L Yu, J Zhu, R Gong - Reactive and Functional Polymers, 2021 - Elsevier
In this paper, a novel grafted polymer (folate and carboxymethyl-β-cyclodextrin grafted
trimethyl chitosan, FCT) was synthesized. Then the FCT nanoparticles (FCT NPs) were …

Tuning the pharmacokinetics and efficacy of irinotecan (IRI) loaded gelatin nanoparticles through folate conjugation

RP Das, S Chakravarti, SS Patel, P Lakhamje… - International Journal of …, 2020 - Elsevier
Gelatin based nanocarriers have major limitation of shorter circulation half-life (t 1/2).
Present study addressed this issue by conjugating gelatin with folate followed by …