Cytosolic delivery of innate immune agonists
Solute carrier proteins (SLCs) are pivotal for maintaining cellular homeostasis by
transporting small molecules across cellular membranes. Recent discoveries have …
transporting small molecules across cellular membranes. Recent discoveries have …
Bacterial peptidoglycan as a living polymer
AM El-Araby, JF Fisher, S Mobashery - Current Opinion in Chemical …, 2025 - Elsevier
The peptidoglycan manifests as a multifaceted component of the bacterial cell wall.
Throughout the lifecycle of the bacterium, the peptidoglycan is deconstructed, rebuilt, and …
Throughout the lifecycle of the bacterium, the peptidoglycan is deconstructed, rebuilt, and …
Targeting Solute Carrier Transporters (SLCs) as a Therapeutic Target in Different Cancers
Solute carrier (SLC) transporters constitute a vast superfamily of transmembrane proteins
tasked with regulating the transport of various substances such as metabolites, nutrients …
tasked with regulating the transport of various substances such as metabolites, nutrients …
Methotrexate suppresses psoriatic skin inflammation by inhibiting muropeptide transporter SLC46A2 activity
Cytosolic innate immune sensing is critical for protecting barrier tissues. NOD1 and NOD2
are cytosolic sensors of small peptidoglycan fragments (muropeptides) derived from the …
are cytosolic sensors of small peptidoglycan fragments (muropeptides) derived from the …