Huntington's disease is the most frequent autosomal dominant neurodegenerative disorder;
however, no disease-modifying interventions are available for patients with this disease. The …

Polyglutamine diseases are a collection of nine CAG trinucleotide expansion disorders,
presenting with a spectrum of neurological and clinical phenotypes. Recent human, mouse …

The human microbiome is an integral component of the human body and a co-determinant
of several health conditions,. However, the extent to which interpersonal relations shape the …

Huntington's disease (HD) is a neurodegenerative disorder caused by the aggregation of
the mutant huntingtin (mHTT) protein in nerve cells. mHTT self-aggregates to form soluble …

Neurodegenerative diseases represent a large group of neurological disorders including
Alzheimer's disease, amyotrophic lateral sclerosis, Parkinson's disease, and Huntington's …

Parkinson's disease is a complex neurodegenerative disease characterized by progressive
movement impairments. Predominant symptoms encompass resting tremor, bradykinesia …

Huntington's disease results from expansion of a polyglutamine tract (polyQ) in mutant
huntingtin (mHTT) protein, but mechanisms underlying polyQ expansion-mediated toxic gain …

Huntington's disease (HD) is caused by an expansion of a CAG repeat in the gene that
encodes the huntingtin protein (HTT). The exact function of HTT is still not fully understood …

Conspectus Huntington's disease (HD) is a progressive, familial neurodegenerative disease
triggered by the expansion of a polyglutamine (polyQ) track in the protein huntingtin (htt) …

Huntington's disease (HD) is one of neurodegenerative diseases, and is defined as a
monogenetic disease due to the mutation of Huntingtin gene. This disease affects several …