Objective: The quantification of inspiratory patient effort in assisted mechanical ventilation is
essential for the adjustment of ventilatory assistance and for assessing patient-ventilator …

The definition of airway resistance is the change in transpulmonary pressure needed to
produce a unit flow of gas through the airways of the lung. More simply put, it is the pressure …

Background: Mechanical ventilation is a critical but resource-intensive treatment. Automated
tools are common in screening diagnostics, whereas real-time, continuous trend analysis in …

Measuring respiratory resistance and elastance as a function of time, tidal volume,
respiratory rate, and positive end-expiratory pressure can guide mechanical ventilation …

In mechanically ventilated patients, some lung injuries can be reduced or avoided with
therapy individualization, while the lung function is evaluated continuously, breath by breath …

Non-invasive estimation of respiratory physiology using computational algorithms promises
to be a valuable technique for future clinicians to detect detrimental changes in patient …

Acute respiratory distress syndrome (ARDS) is a severe form of acute hypoxemic respiratory
failure affecting 10% of patients admitted to the intensive care unit (ICU) globally. In-hospital …

In this paper we present a method for the estimation of leaks in non-invasive ventilation.
Accurate estimation of leaks is a key component of a ventilator, since it determines the …

Esophageal pressure is currently seen as the gold standard to quantify the respiratory effort
during assisted spontaneous ventilation. Yet, the assessment of waveforms at the bedside is …

Typical modern mechanical ventilators offer the clinician the possibility of automatically
performing end-inspiratory occlusion maneuvers. The static conditions induced by such …