CDKL5 deficiency disorder (CDD) was first identified as a cause of human disease in 2004.
Although initially considered a variant of Rett syndrome, CDD is now recognised as an …

This review aims to provide an updated perspective of epilepsy genetics and precision
medicine in adult patients, with special focus on developmental and epileptic …

Background CDKL5 deficiency disorder (CDD) is associated with refractory infantile onset
epilepsy, global developmental delay, and variable features that include sleep, behavioral …

CDKL5 Deficiency Disorder (CDD) is a rare, X-linked dominant condition that causes a
developmental and epileptic encephalopathy (DEE). The incidence is between~ 1: 40,000 …

Abstract Cyclin-dependent kinase-like 5 (CDKL5) deficiency disorder (CDD) is a
developmental and epileptic encephalopathy with infantile-onset epilepsy. Most individuals …

Many neurodevelopmental disorders (NDDs) are the result of mutations on the X
chromosome. One severe NDD resulting from mutations on the X chromosome is CDKL5 …

Background and Objective CDKL5 deficiency disorder presents as a challenging condition
with early-onset refractory seizures, severe developmental delays, and a range of other …

The redefinition of classical electroclinical syndromes and the emergence of neurogenetics
has led to a revolution in the field of developmental and epileptic encephalopathies (DEEs) …

Abstract Cyclin‐dependent kinase‐like 5 (CDKL5) deficiency disorder (CDD) is a
developmental and epileptic encephalopathy caused by variants in the CDKL5 gene. The …

ABSTRACT Introduction Cyclin-dependent kinase-Like 5 (CDKL5) deficiency disorder
(CDD) is a rare neurodevelopmental condition commonly characterized by drug-resistant …