Novel treatment strategies for biofilm-based infections

C Vuotto, G Donelli - Drugs, 2019 - Springer
Biofilm-growing cells show an enhanced antimicrobial tolerance with respect to the same
cells growing in a free-floating way. This is due to physical or chemical diffusion barriers and …

Otitis media pathogens–A life entrapped in biofilm communities

MD Silva, S Sillankorva - Critical reviews in microbiology, 2019 - Taylor & Francis
Otitis media is a group of inflammatory diseases of the middle ear with great impact on
children worldwide. The most common reported bacterial pathogens are Streptococcus …

The majority of microorganisms in gas hydrate-bearing subseafloor sediments ferment macromolecules

C Zhang, YX Fang, X Yin, H Lai, Z Kuang, T Zhang… - Microbiome, 2023 - Springer
Background Gas hydrate-bearing subseafloor sediments harbor a large number of
microorganisms. Within these sediments, organic matter and upward-migrating methane are …

The Moraxella catarrhalis phase-variable DNA methyltransferase ModM3 is an epigenetic regulator that affects bacterial survival in an in vivo model of otitis media

LV Blakeway, A Tan, JA Jurcisek, LO Bakaletz… - BMC microbiology, 2019 - Springer
Background Moraxella catarrhalis is a leading cause of otitis media (OM) and chronic
obstructive pulmonary disease (COPD). M. catarrhalis contains a Type III DNA adenine …

Panel 7–pathogenesis of otitis media–a review of the literature between 2015 and 2019

RB Thornton, A Hakansson, DW Hood… - International journal of …, 2020 - Elsevier
Objective To perform a comprehensive review of the literature from July 2015 to June 2019
on the pathogenesis of otitis media. Bacteria, viruses and the role of the microbiome as well …

Multitasking functions of bacterial extracellular DNA in biofilms

DK Sharma, YS Rajpurohit - Journal of Bacteriology, 2024 - Am Soc Microbiol
Bacterial biofilms are intricate ecosystems of microbial communities that adhere to various
surfaces and are enveloped by an extracellular matrix composed of polymeric substances …

Studies on Bd0934 and Bd3507, Two Secreted Nucleases from Bdellovibrio bacteriovorus, Reveal Sequential Release of Nucleases during the Predatory Cycle

E Bukowska-Faniband, T Andersson… - Journal of …, 2020 - Am Soc Microbiol
Bdellovibrio bacteriovorus is an obligate predatory bacterium that invades and kills a broad
range of Gram-negative prey cells, including human pathogens. Its potential therapeutic …

An up-to-date review on bio-resource therapeutics effective against bacterial species frequently associated with chronic sinusitis and tonsillitis

M Kostić, M Ivanov, SS Babić, J Petrović… - Current Medicinal …, 2020 - ingentaconnect.com
Upper respiratory tract infections include inflammations of the nose, sinuses (sinusitis),
pharynx (tonsillitis, pharyngitis) and larynx (laryngitis) with bacteria or viruses as the main …

Sputum bacterial metacommunities in distinguishing heterogeneity in respiratory health and disease

J Si, Y Choi, J Raes, G Ko, HJ You - Frontiers in Microbiology, 2022 - frontiersin.org
Background and Objective Cluster-based analysis, or community typing, has been
attempted as a method for studying the human microbiome in various body niches with the …

Moraxella catarrhalis

K Yao, D Liu - Molecular Medical Microbiology, 2024 - Elsevier
As a gram-negative diplococcus that commonly resides in human nasopharyngeal cavity as
commensal, Moraxella catarrhalis demonstrates the capacity to take advantage of temporary …