Medication-related osteonecrosis of the jaw (MRONJ) is a potentially severe adverse event
affecting patients with cancer and patients with osteoporosis who have been treated with …

It is well established that alterations in phosphate metabolism have a profound effect on
hard and soft tissues of the oral cavity. The present-day clinical form of osteonecrosis of the …

Zoledronic acid (ZA) is one of the most important and effective class of anti-resorptive drug
available among bisphosphonate (BP), which could effectively reduce the risk of skeletal …

Chronic bone degenerative diseases represent a major threat to the health and well-being
of the population, particularly those with advanced age. This study isolated exosomes …

The mechanism and effective treatment of bisphosphonate-related osteonecrosis of the jaw
(BRONJ) are still uncertain. Our previous study revealed that zoledronate (ZOL) …

Medication-related osteonecrosis of the jaw (MRONJ) has emerged as a complication of anti-
resorptive medications. Despite its low incidence rate, this problem has gained attention in …

Objective To assess the outcomes of several rodent animal models for studying tooth
extraction-related medication-related osteonecrosis of the jaw (MRONJ). Design After a …

Cell reprogramming can satisfy the demands of obtaining specific cell types for applications
such as tissue regeneration and disease modeling. Here we report the reprogramming of …

Dendritic cells are an important link between innate and adaptive immune response. The
role of dendritic cells in bone homeostasis, however, is not understood. Osteoporosis …

Osteoclasts are the primary target for osteoporosis drug development. Recent animal
studies revealed the crucial roles of osteoblasts in regulating osteoclastogenesis and the …