Regulation of airway smooth muscle contraction in health and disease

M Lam, E Lamanna, JE Bourke - Smooth muscle spontaneous activity …, 2019 - Springer
Airway smooth muscle (ASM) extends from the trachea throughout the bronchial tree to the
terminal bronchioles. In utero, spontaneous phasic contraction of fetal ASM is critical for …

Upregulation of LncRNA Malat1 Induced Proliferation and Migration of Airway Smooth Muscle Cells via miR-150-eIF4E/Akt Signaling

L Lin, Q Li, W Hao, Y Zhang, L Zhao, W Han - Frontiers in physiology, 2019 - frontiersin.org
The increased proliferation and migration of airway smooth muscle cells (ASMCs) are critical
processes in the formation of airway remodeling in asthma. Long non-coding RNAs …

[HTML][HTML] Stressed out-The role of oxidative stress in airway smooth muscle dysfunction in asthma and COPD

RM Saunders, M Biddle, Y Amrani… - Free Radical Biology and …, 2022 - Elsevier
The airway smooth muscle (ASM) surrounding the airways is dysfunctional in both asthma
and chronic obstructive pulmonary disease (COPD), exhibiting; increased contraction …

Regulation of smooth muscle contraction by the epithelium: role of prostaglandins

YC Ruan, W Zhou, HC Chan - Physiology, 2011 - journals.physiology.org
As an analog to the endothelium situated next to the vascular smooth muscle, the epithelium
is emerging as an important regulator of smooth muscle contraction in many vital …

Airway smooth muscle and immunomodulation in acute exacerbations of airway disease

CJ Koziol‐White, RA Panettieri Jr - Immunological reviews, 2011 - Wiley Online Library
Airway smooth muscle (ASM) manifests a hyperresponsive phenotype in airway disorders
such as asthma, chronic obstructive pulmonary disease (COPD), and cystic fibrosis. Current …

Inhaled house dust mite induces pulmonary T helper 2 cytokine production

LG Gregory, B Causton, JR Murdoch… - Clinical & …, 2009 - Wiley Online Library
Background Inhaled house dust mite (HDM) results in T‐helper (TH) 2 type pathology in
unsensitized mice, in conjunction with airway hyperreactivity and airway remodelling …

Does airway smooth muscle express an inflammatory phenotype in asthma?

G Damera, RA Panettieri, Jr - British journal of pharmacology, 2011 - Wiley Online Library
In addition to hyperresponsiveness in asthma, airway smooth muscle (ASM) also manifests
an inflammatory phenotype characterized by augmented expression of mediators that …

Pharmacology and immunological actions of a herbal medicine ASHMITM on allergic asthma

T Zhang, K Srivastava, MC Wen, N Yang… - Phytotherapy …, 2010 - Wiley Online Library
Allergic asthma is a chronic and progressive inflammatory disease for which there is no
satisfactory treatment. Studies reported tolerability and efficacy of an anti‐asthma herbal …

Inflammatory markers in childhood asthma

S Dodig, D Richter, R Zrinski-Topić - Clinical chemistry and …, 2011 - degruyter.com
The major characteristic of asthma is persistent airway inflammation that fails to resolve
spontaneously. Dysregulation of pro-and anti-inflammatory mechanisms is responsible for …

Macromolecular biomarkers of chronic obstructive pulmonary disease in exhaled breath condensate

S Kazeminasab, B Emamalizadeh… - Biomarkers in …, 2020 - Taylor & Francis
Biomarkers provide important diagnostic and prognostic information on heterogeneous
diseases such as chronic obstructive pulmonary disease (COPD). However, finding a …