Many factors such as trauma and COVID-19 cause acute kidney injury (AKI). Late AKI have
a very high incidence and mortality rate. Early diagnosis of AKI provides a critical therapeutic …

Albuminuria is a hallmark of glomerular disease of various etiologies. It is not only a
symptom of glomerular disease but also a cause leading to glomerulosclerosis, interstitial …

FLASH radiotherapy is attracting increasing interest because it maintains tumor control while
inflicting less damage to normal tissues compared to conventional radiotherapy. This …

Misfolded protein aggregates may cause toxic proteinopathy, including autosomal dominant
tubulointerstitial kidney disease due to uromodulin mutations (ADTKD-UMOD), a leading …

High-redox-potential reactive oxygen species and reactive nitrogen species (ROS/RNS),
generated by NADPH oxidase-2 (NOX2), myeloperoxidase (MPO) and related enzymes, are …

Breast cancer bone metastases are common and incurable. Tumoral integrin β3 (β3)
expression is induced through interaction with the bone microenvironment. Although β3 is …

Inflammation is an important component of several chronic and debilitating diseases that
result in significant morbidity and mortality. This is best evidenced within the cardiovascular …

Reactive oxygen species (ROS) are closely associated with the progression of diabetic
cardiomyopathy (DCM) and can be regarded as one of its early biomarkers. Magnetic …

Oxidative stress is the imbalance of harmful reactive oxygen species (ROS) and the action of
neutralizing antioxidant mechanisms. If left unchecked, the deleterious effects of oxidative …

Doxorubicin (DOX) induces dose-dependent cardiotoxicity via oxidative stress and
abnormal mitochondrial function in the myocardium. Therefore, a noninvasive in vivo …