Calreticulin from parasites and its vertebrate hosts share~ 50% identity and many of its
functions are equally conserved. However, the existing amino acid differences can affect its …

Because of its capacity to increase a physiologic inflammatory response, to stimulate
phagocytosis, to promote cell lysis and to enhance pathogen immunogenicity, the …

Introduction Human adipose-derived mesenchymal stem cells (ADMSCs) with their
secretory factors are able to induce collagen synthesis and fibroblast migration in the wound …

Topical application of extracellular calreticulin (eCRT), an ER chaperone protein, in animal
models enhances wound healing and induces tissue regeneration evidenced by epidermal …

A novel real-time optical phase sensing method based on the Mach-Zehnder interference
principle has been proposed for the detection of calreticulin (CRT) levels in human serum …

To successfully infect, Trypanosoma cruzi evades and modulates the host immune
response. T. cruzi calreticulin (TcCalr) is a multifunctional, endoplasmic reticulum (ER) …

American Trypanosomiasis, a parasitic disease produced by Trypanosoma cruzi (T. cruzi),
endemic in Latin America, infects about 6 million people. During the chronic stage of the …

Toxoplasma gondii, a highly prevalent apicomplexan pathogen, can cause serious or even
fatal toxoplasmosis in both animals and humans. Immunoprophylaxis is considered a …

Radiotherapy is a primary treatment modality for many malignancies. In head and neck
cancer (HNC), patients with early-stage disease are treated with surgery and radiation, while …

Calreticulin (CRT), initially described as an endoplasmic reticulum (ER)-resident chaperone
with high affinity for Ca2+, also localizes in the nucleus, cytoplasm, plasma membrane and …