Neuroprotective Activity of Hypericum perforatum and Its Major Components

AI Oliveira, C Pinho, B Sarmento… - Frontiers in plant …, 2016 - frontiersin.org
Hypericum perforatum is a perennial plant, with worldwide distribution, commonly known as
St. John's wort. It has been used for centuries in traditional medicine for the treatment of …

Hypericum perforatum: Pharmacokinetic, Mechanism of Action, Tolerability, and Clinical Drug–Drug Interactions

E Russo, F Scicchitano, BJ Whalley… - Phytotherapy …, 2014 - Wiley Online Library
Hypericum perforatum (HP) belongs to the Hypericaceae family and is one of the oldest
used and most extensively investigated medicinal herbs. The medicinal form comprises the …

Drug interactions with herbal medicines

S Shi, U Klotz - Clinical pharmacokinetics, 2012 - Springer
In recent years, the issue of herbal medicine-drug interactions has generated significant
concern. Such interactions can increase the risk for an individual patient, especially with …

Enzyme activity of natural products on cytochrome P450

HL Zuo, HY Huang, YCD Lin, XX Cai, XJ Kong, DL Luo… - Molecules, 2022 - mdpi.com
Drug-metabolizing enzymes, particularly the cytochrome P450 (CYP450) monooxygenases,
play a pivotal role in pharmacokinetics. CYP450 enzymes can be affected by various …

Differences between dietary supplement and prescription drug omega-3 fatty acid formulations: a legislative and regulatory perspective

N Collins, AP Tighe, SA Brunton… - Journal of the American …, 2008 - Taylor & Francis
The medical management of many diseases and conditions can include either restriction or
provision of specific essential nutrients. When such nutrients are needed, there are often …

The induction of CYP1A2, CYP2D6 and CYP3A4 by six trade herbal products in cultured primary human hepatocytes

BH Hellum, Z Hu, OG Nilsen - Basic & clinical pharmacology & …, 2007 - Wiley Online Library
The aim of this study was to evaluate the in vitro inductive potential of six commonly used
trade herbal products on CYP1A2, CYP2D6 and CYP3A4 metabolic activities. Herbal …

Pharmacokinetic interactions between herbal medicines and prescribed drugs: focus on drug metabolic enzymes and transporters

Q Meng, K Liu - Current Drug Metabolism, 2014 - ingentaconnect.com
Herbal medicines have been widely used for thousands of years, and now are gaining
continued popularity worldwide as a complementary or alternative treatment for a variety of …

An update on the ability of St. John's wort to affect the metabolism of other drugs

R Rahimi, M Abdollahi - Expert opinion on drug metabolism & …, 2012 - Taylor & Francis
Introduction: Hypericum perforatum (HP), more commonly known as St. John's wort, is a
popular medicinal herb used for the treatment of depression. HP affects the …

Drug—Botanical Interactions: A Review of the Laboratory, Animal, and Human Data for 8 Common Botanicals

SS Shord, K Shah, A Lukose - Integrative cancer therapies, 2009 - journals.sagepub.com
Many Americans use complementary and alternative medicine (CAM) to prevent or alleviate
common illnesses, and these medicines are commonly used by individuals with cancer …

Um alerta sobre o uso de produtos de origem vegetal na gravidez

JHR Clarke, SMK Rates, R Bridi - Infarma-Ciências …, 2007 - cff.emnuvens.com.br
No Brasil, o uso de plantas medicinais é amplamente difundido e a maior parte dos
fitoterápicos comercializados é de venda sem prescrição médica. A população que utiliza …