Nonsteroidal anti-inflammatory drugs (NSAIDs) are increasingly employed in ophthalmology
to reduce miosis and inflammation, manage scleritis, and prevent and treat cystoid macular …

Uveal melanoma is the most common primary intra-ocular malignancy in adults. Overall
mortality rate remains high because of the development of metastatic disease, which is …

Abstract BACKGROUND: Forkhead box P3 (FOXP3)‐positive regulatory T cells (Tregs) are
key mediators of peripheral tolerance and suppress efficient antitumor responses …

The work outlined herein describes AU-011, a novel recombinant papillomavirus-like
particle (VLP) drug conjugate and its initial evaluation as a potential treatment for primary …

In the presence of 12-O-tetradecanoylphorbol-13-acetate (TPA) stimulation, an increase in
the migration/invasion of U87 glioblastoma cells was detected by a wound healing assay …

Animal models serve as powerful tools for investigating the pathobiology of cancer,
identifying relevant pathways, and developing novel therapeutic agents. They have …

There is now increasing evidence that a constitutive expression of cyclooxygenase 2 (COX-
2) plays a role in the development and progression of malignant ectodermal tumours. In this …

Introduction: Nonsteroidal anti-inflammatory drugs (NSAIDs) are one of the most commonly
prescribed medications and are routinely used for their analgesic, antipyretic, and anti …

Purpose.: In contrast to many malignancies showing evidence that interleukin-1 (IL-1)
promotes progression through effects on tumor vascularity and myeloid suppressor cell …

Background Ocular melanoma is easily treated by the removal of the eye or through plaque
radiotherapy. However, after removal or control of the primary tumor, patients can develop …