Compared with stainless steel and Co–Cr‐based alloys, Ti and its alloys are widely used as
biomedical implants due to many fascinating properties, such as superior mechanical …

Skeletal disorders are among the leading debilitating factors affecting millions of people
worldwide. The use of stem cells for tissue repair has raised many promises in various …

The two leading causes of failure for joint arthroplasty prostheses are aseptic loosening and
periprosthetic joint infection. With the number of primary and revision joint replacement …

Wnt signaling plays a central regulatory role across a remarkably diverse range of functions
during embryonic development, including those involved in the formation of bone and …

Healing and regeneration of bone injuries, particularly those that are associated with large
bone defects, are a complicated process. There is growing interest in the application of …

During bone modeling, remodeling, and bone fracture repair, mesenchymal stem cells
(MSCs) differentiate into chondrocyte or osteoblast to comply bone formation and …

Over the past 2 decades, mesenchymal stem cells (MSCs) have attracted a lot of interest as
a unique therapeutic approach for a variety of diseases. MSCs are capable of self-renewal …

Cell therapy continues to attract growing interest as a promising approach to treat a variety
of diseases. Mesenchymal stem cells (MSCs) have been one of the most intensely studied …

The increasing demand for orthopedic implants has driven the search for materials that
combine strength, biocompatibility, and long lifetime. Compared to stainless steel and Co-Cr …

A significant challenge in the current orthopedics is the development of suitable
osteobiologic materials that can replace the conventional allografts, autografts, and …