During nervous system development, neurons extend axons to reach their targets and form
functional circuits. The faulty assembly or disintegration of such circuits results in disorders …

In mammals, excitatory cortical neurons develop from the proliferative epithelium and
progenitor cells in the ventricular zone and subventricular zone, and migrate radially to the …

Recent studies have reported that complement-related proteins modulate brain
development through regulating synapse processes in the cortex. CSMD3 belongs to a …

The human brain is the most complex structure generated during development. Unveiling
the ontogenesis and the intrinsic organization of specific neural networks may represent a …

Correct wiring in the neocortex requires that responses to an individual guidance cue vary
among neurons in the same location, and within the same neuron over time. Nestin is an …

Loss-of-function mutations in chromatin remodeler gene ARID1A are a cause of Coffin-Siris
syndrome, a developmental disorder characterized by dysgenesis of corpus callosum. Here …

Neural circuit development involves the coordinated growth and guidance of axons to their
targets. Following the identification of many guidance cue molecules, recent experiments …

The current model, based on rodent data, proposes that thalamocortical afferents (TCA)
innervate the subplate towards the end of cortical neurogenesis. This implies that the …

Abstract The BTBR T+ Itpr3 tf/J (BTBR/J) strain is one of the most valid models of idiopathic
autism, serving as a potent forward genetics tool to dissect the complexity of autism. We …

Amniotic fluid has been proposed as an easily available source of cells for numerous
applications in regenerative medicine and tissue engineering. The use of amniotic fluid cells …