Applications of sesquiterpene lactones: a review of some potential success cases

L Moujir, O Callies, PMC Sousa, F Sharopov… - Applied Sciences, 2020 - mdpi.com
Sesquiterpene lactones, a vast range of terpenoids isolated from Asteraceae species,
exhibit a broad spectrum of biological effects and several of them are already commercially …

Plant-derived natural products in cancer research: extraction, mechanism of action, and drug formulation

WH Talib, I Alsalahat, S Daoud, RF Abutayeh… - Molecules, 2020 - mdpi.com
Cancer is one of the main causes of death globally and considered as a major challenge for
the public health system. The high toxicity and the lack of selectivity of conventional …

Trends in parthenolide research over the past two decades: a bibliometric analysis

J Liu, M Cui, Y Wang, J Wang - Heliyon, 2023 - cell.com
Parthenolide (PTL) is a new compound extracted from traditional Chinese medicine. In
recent years, it has been proven to play an undeniable role in tumors, autoimmune …

The therapeutic effect and mechanism of parthenolide in skeletal disease, cancers, and cytokine storm

S Zhu, P Sun, S Bennett, O Charlesworth… - Frontiers in …, 2023 - frontiersin.org
Parthenolide (PTL or PAR) was first isolated from Magnolia grandiflora and identified as a
small molecule cancer inhibitor. PTL has the chemical structure of C15H20O3 with …

[HTML][HTML] Palmyra and coconut haustorium: a comprehensive review on nutritional composition, bioactive potential, value-added products and its health benefits

ER Rajeshwari, PS Sathanya, S Vignesh… - Food Chemistry …, 2024 - Elsevier
The various parts of the palmyra and coconut trees which are widely distributed in the
southern parts of the Indian subcontinent have been studied and utilized for many years …

Immune-relevant aspects of murine models of head and neck cancer

C Rossa Jr, NJ D'Silva - Oncogene, 2019 - nature.com
Head and neck cancers (HNCs) cause significant mortality and morbidity. There have been
few advances in therapeutic management of HNC in the past 4 to 5 decades, which support …

Parthenolide and its analogues: a new potential strategy for the treatment of triple-negative breast tumors

TG Araujo, L Vecchi, PMAP Lima… - Current Medicinal …, 2020 - ingentaconnect.com
Triple Negative Breast Cancers (TNBC) are heterogeneous and aggressive pathologies,
with distinct morphological and clinical characteristics associated with their genetic diversity …

PLGA‐Loaded Nedaplatin (PLGA‐NDP) Inhibits 7, 12‐Dimethylbenz [a] anthracene (DMBA) Induced Oral Carcinogenesis via Modulating Notch Signaling Pathway …

S Ilanchit Chenni, K Suresh, A Theerthu… - Cell Biochemistry …, 2024 - Wiley Online Library
The present study is designed to evaluate the nanotherapeutic efficacy of prepared PLGA‐
loaded Nedaplatin (PLGA‐NDP) against 7, 12‐dimethyl benz (a) anthracene (DMBA) …

LRP5, SLC6A3, and SOX10 Expression in Conventional Ameloblastoma

L Correa-Arzate, J Portilla-Robertson… - Genes, 2023 - mdpi.com
Cell proliferation and invasion are characteristic of many tumors, including ameloblastoma,
and are important features to target in possible future therapeutic applications. Objective …

Head and neck cancer prevention by phytochemicals: Current status and challenges

VK Nimbalkar, S Manna, GB Maru… - Current Pharmacology …, 2020 - Springer
Cancer is a growing health concern worldwide associated with a rise in life expectancy,
lifestyle, and environmental exposures. In India, head and neck squamous cell carcinomas …