Microorganisms have evolved to thrive in virtually any terrestrial and marine environment,
exposing them to various mechanical cues mainly generated by fluid flow and pressure as …

Profound changes are occurring in the strategies that biotechnology-based industries are
deploying in the search for exploitable biology and to discover new products and develop …

Pressures between 10 and 100 MPa can exert powerful effects on the growth and viability of
organisms. Here I describe the effects of elevated pressure in this range on mesophilic …

The transmembrane transcriptional activators ToxR and TcpP modulate expression of Vibrio
cholerae virulence factors by exerting control over toxT, which encodes the cytoplasmic …

Covering: up to the end of 2007 This review covers the 390 novel marine natural products
described to date from deep-water (> 50 m) marine fauna, with details on the source …

Microorganisms that prefer high-pressure conditions are termed piezophiles (previously
termed barophiles). The molecular basis of piezophily is now being investigated extensively …

There has been a renewal of interest in the survival strategies employed by deep-sea, high-
pressure-adapted (piezophilic) microorganisms as well as in the effects of high pressure on …

Two-thirds of Earth's surface is covered by oceans, yet the study of this massive integrated
living system is still in its infancy. Various environmental variables, such as high salinity, low …

Hydrostatic pressure is a well-known physical parameter which is now considered an
important variable of life, since organisms have the ability to adapt to pressure changes, by …

The transmembrane regulatory protein ToxR is required for expression of virulence factors in
the human diarrheal pathogen Vibrio cholerae, including cholera toxin (CT) and the toxin …