Exposure of cells to high voltage electric pulses increases transiently membrane
permeability through membrane electroporation. Electroporation can be reversible and is …

Radiation therapy (RT) is responsible for at least 40% of cancer cures, however treatment
resistance remains a clinical problem. There have been recent advances in understanding …

Inflammatory gene expression following genotoxic cancer therapy is well documented, yet
the events underlying its induction remain poorly understood. Inflammatory cytokines modify …

During the last few decades, improvements in the planning and application of radiotherapy
in combination with surgery and chemotherapy resulted in increased survival rates of tumor …

Technological developments have allowed improvements in radiotherapy delivery, with
higher precision and better sparing of normal tissue. For many years, it has been well known …

The metabolism of oxygen, although central to life, produces reactive oxygen species (ROS)
that have been implicated in processes as diverse as cancer, cardiovascular disease and …

In recent years remarkable progress has been made towards the understanding of proposed
hallmarks of cancer development and treatment. However with its increasing incidence, the …

The main goal when treating malignancies with radiation therapy is to deprive tumor cells of
their reproductive potential. One approach to achieve this is by inducing tumor cell …

Multiple pathways are involved in maintaining the genetic integrity of a cell after its exposure
to ionizing radiation. Although repair mechanisms such as homologous recombination and …

The ability of engineered cerium oxide nanoparticles to confer radioprotection was
examined. Human normal and tumor cells were treated with nanoceria and irradiated, and …