The metabolism and biotransformation of AFB1: Key enzymes and pathways

L Wang, Q Huang, J Wu, W Wu, J Jiang, H Yan… - Biochemical …, 2022 - Elsevier
Abstract Aflatoxins B 1 (AFB 1) is a hepatoxic compound produced by Aspergillus flavus and
Aspergillus parasiticus, seriously threatening food safety and the health of humans and …

Degradation of aflatoxin B1 by a recombinant laccase from Trametes sp. C30 expressed in Saccharomyces cerevisiae: A mechanism assessment study in vitro and in …

Y Liu, H Mao, KW Yohannes, Z Wan, Y Cao… - Food Research …, 2021 - Elsevier
Abstract Aflatoxin B 1 (AFB 1) is the most harmful mycotoxin and presents risks to human
health. Utilization of enzyme to degrade AFB1 is a promising strategy to overcome this …

Molecular docking studies and in vitro degradation of four aflatoxins (AFB1, AFB2, AFG1, and AFG2) by a recombinant laccase from Saccharomyces cerevisiae

Y Liu, H Mao, C Hu, T Tron, J Lin, J Wang… - Journal of food …, 2020 - Wiley Online Library
Here, molecular docking simulation was used to predict and compare interactions between
a recombinant Trametes sp. C30 laccase from Saccharomyces cerevisiae and four …

Probing the Surface of a Laccase for Clues towards the Design of Chemo‐Enzymatic Catalysts

V Robert, E Monza, L Tarrago, F Sancho… - …, 2017 - Wiley Online Library
Abstract Systems featuring a multi‐copper oxidase associated with transition‐metal
complexes can be used to perform oxidation reactions in mild conditions. Here, a strategy is …

Activity enhancement of CotA laccase by hydrophilic engineering, histidine tag optimization and static culture

L Li, T Xie, Z Liu, H Feng, G Wang - Protein Engineering, Design …, 2018 - academic.oup.com
CotA protein from Bacillus subtilis is of laccase activity. The solubility of recombinant CotA is
low, which hinders its application. In this study, histidine tag position optimization and …

Production and manipulation of blue copper oxidases for technological applications

S Zhou, P Rousselot-Pailley, L Ren… - Methods in …, 2018 - Elsevier
Fungal laccases are robust multicopper oxidoreductases. Perfectly amenable to synthetic
evolution, the fungal laccase scaffold is a potential generic for the production of tailored …

Molecular docking analysis of the interaction between recombinant laccase and Af 1 atoxin B1 and structural elucidation of degradation products of Af 1 atoxin B1.

Y Liu, H Mao, Z Yang, Z Wan, J Wang, B Sun - 2019 - cabidigitallibrary.org
In the present research, 3KW7 with the highest homology to the laccase lac3 gene was
selected as a template for homology modeling, and molecular docking was used to predict …

Effectors of selectivity in laccase catalyzed reactions

L Ren - 2019 - theses.hal.science
Laccases are multicopper oxidases produced by fungi, bacteria as well as plants and
insects. These enzymes are coupling the neat four electrons/four protons reduction of …

Molecular and Genetic Strategies for Enhanced Production of Heterologous Lignocellulosic Enzymes

SA Comyn, JK Magnuson - Grand Challenges in Fungal Biotechnology, 2020 - Springer
A desire to move away from fossil fuels toward more sustainable, renewable, or carbon-
neutral sources has motivated the search for alternative feedstocks. Lignocellulosic biomass …

[PDF][PDF] C5790 Production and manipulation of blue copper oxidases for technological applications

S Zhou, P Rousselot-Pailley, L Ren, Y Charmasson… - 1918 - academia.edu
Fungal laccases are robust multicopper oxidoreductases. Perfectly amenable to synthetic
evolution, the fungal laccase scaffold is a potential generic for the production of tailored …