Epigenetic changes associated with different types of stressors and suicide

G Dee, R Ryznar, C Dee - Cells, 2023 - mdpi.com
Stress is associated with various epigenetic changes. Some stress-induced epigenetic
changes are highly dynamic, whereas others are associated with lasting marks on the …

[HTML][HTML] Epigenetic Alterations in Post-Traumatic Stress Disorder: Comprehensive Review of Molecular Markers

E Golubeva, A Zeltser, Y Zorkina, A Ochneva… - Complex …, 2024 - karger.com
Background: Post-traumatic stress disorder (PTSD) can occur after a traumatic event. PTSD
is characterized by nightmares, flashbacks and avoidance of stressors. It currently affects 2 …

Maternal adverse childhood experiences (ACEs) and offspring imprinted gene DMR methylation at birth

AC Vidal, DW Sosnowski, J Marchesoni, C Grenier… - Epigenetics, 2024 - Taylor & Francis
Adverse childhood experiences (ACEs) contribute to numerous negative health outcomes
across the life course and across generations. Here, we extend prior work by examining the …

Prenatal exposure to genocide and subsequent adverse childhood events are associated with DNA methylation of SLC6A4, BDNF, and PRDM8 in early adulthood …

LM Rivera, G Uwizeye, H Stolrow, B Christensen… - Scientific Reports, 2024 - nature.com
We investigated associations between prenatal genocidal trauma, including maternal rape,
and postnatal adverse childhood experiences (ACEs) on DNA methylation of genes …

Family Therapy for Kosovar Mothers Who Experienced Conflict‐Related Sexual Violence and Their Children in Postwar Times: A Pilot Randomised Waitlist …

C Seery, F Rushiti, SP Krasniqi… - Clinical psychology …, 2024 - Wiley Online Library
Women who have experienced conflict‐related sexual violence report significant long‐term
effects, including posttraumatic stress disorder (PTSD), depression and relationship …

Detection of DNA methylation from buccal swabs using nanopore sequencing to study stunting

A El-Hakim, I Cahyani, MZ Arief, G Akbariani… - Epigenetics, 2024 - Taylor & Francis
Stunting is the result of chronic malnutrition due to the lack of micronutrient-based methyl
donors required for epigenetic programming during the first 1000 days of life. Methylation …

An epigenome‐wide study of a needs‐based family intervention for offspring of trauma‐exposed mothers in Kosovo

J Ryan, AZZ Phyo, SP Krasniqi, SI Carkaxhiu… - Brain and …, 2024 - Wiley Online Library
Introduction Maternal stress and trauma during pregnancy have been shown to influence
cortisol levels and epigenetic patterns, including DNA methylation, in the offspring. This …

Association of hair cortisol concentration with brain‐derived neurotrophic factor gene methylation: The role of sex as a moderator

Z Li, W Kong, HY Park, SJ Koo, M Bang… - Stress and …, 2024 - Wiley Online Library
Hair cortisol concentration (HCC) reflects the long‐term activity of the hypothalamus‐
pituitary‐adrenal (HPA) axis in response to stress. Brain‐derived neurotrophic factor DNA …

Associations of DNA methylation of HPA axis-related genes and neuroendocrine abnormalities in panic disorder

Z Zou, M Xiang, Y Zhang, Y Huang, J Wang… - …, 2022 - Elsevier
Objective The purpose of this study was to investigate the role of aberrant DNA methylation
of hypothalamic-pituitary-adrenal (HPA) axis-related genes (CRHR1, CRHR2, CRH, FKBP5 …

The impact on child development of traumatic exposure during pregnancy: a systematic review

L Colamarino, C Salvagno, A Soubelet - European Journal of Trauma & …, 2024 - Elsevier
Psychotrauma during the antenatal period seems to have consequences for children's
physical and mental health. This systematic review aims to assess the impact of traumatic …