Hepatic macrophage populations include different types of cells with plastic properties that
can differentiate into diverse phenotypes to modulate their properties in response to different …

Investigational long-acting injectable nanoformulations of rilpivirine and GSK1265744 are
clinical-stage development candidates. Complementary pharmacologic properties of both …

Cell-based therapy is a promising modality to address many unmet medical needs. In
addition to genetic engineering, material-based, biochemical, and physical science-based …

Long-acting formulations are designed to reduce dosing frequency and simplify dosing
schedules by providing an extended duration of action. One approach to obtain long-acting …

In spite of significant advances in antiretroviral (ARV) therapy, the elimination of human
immunodeficiency virus (HIV) reservoirs from the periphery and the central nervous system …

Site-specific delivery of antibiotics has always been a high-priority area in pharmaceutical
research. Conventionally used antibiotics suffer several limitations, such as low …

The discipline of neurotheranostics was forged to improve diagnostic and therapeutic
clinical outcomes for neurological disorders. Research was facilitated, in largest measure …

The appearance and rapid spread of drug resistant strains of tuberculosis (TB), one of the
deadliest infectious diseases, pose a serious threat to public health and increase the need …

Reactive oxygen species (ROS)-responsive nanomedicine has been extensively developed
to improve the therapeutic effects while reducing the systemic toxicity. ROS, as important …

Background Immunocompromised individuals and those with lung dysfunction readily
acquire pulmonary bacterial infections, which may cause serious diseases and carry a …