Early immune and host cell responses to Cryptosporidium infection

JR Mead - Frontiers in parasitology, 2023 - frontiersin.org
Cryptosporidium spp. are opportunistic protozoan parasites that infect epithelial cells of the
small intestine and cause diarrheal illness in both immunocompetent and immunodeficient …

[HTML][HTML] Host Immune Response to Cryptosporidium spp.: Insights and Perspectives for Vaccine Development

M Ali, C Xu, Y Ji, K Li - Animals and Zoonoses, 2025 - Elsevier
Cryptosporidium, a zoonotic protozoan parasite, poses a significant threat to both public
health and the livestock sectors globally, leading to lethal diarrheal disease and associated …

Genomic analysis of gastrointestinal parasite resistance in akkaraman sheep

Y Arzik, M Kizilaslan, SN White, LMW Piel, MU Çınar - Genes, 2022 - mdpi.com
Genome-wide association studies (GWAS) have been used as an effective tool to
understand the genetics of complex traits such as gastrointestinal parasite (GIP) resistance …

[HTML][HTML] Is Cryptosporidium a hijacker able to drive cancer cell proliferation?

G Certad - Food and Waterborne Parasitology, 2022 - Elsevier
The pathophysiological mechanisms of Cryptosporidium infection are multifactorial and not
completely understood. Some advances achieved recently revealed that the infection by …

MiR-4521 affects the propagation of Cryptosporidium parvum in HCT-8 cells through targeting foxm1 by regulating cell apoptosis

Q Yao, YY Fan, S Huang, GR Hu, JK Song, X Yang… - Acta tropica, 2024 - Elsevier
Cryptosporidium parvum could regulate the expression of microRNAs of epithelial cells to
facilitate its intracellular propagation. MiR-4521 has been reported to play an important role …

Cryptosporidium parvum downregulates miR-181d in HCT-8 cells via the p50-dependent TLRs/NF-κB pathway

R Feng, Z Niu, X Zhang, W Hou, Y Zhang, F Jian… - Veterinary …, 2022 - Elsevier
Cryptosporidium spp. can cause diarrhea and even death in humans and animals. Host
microRNAs (miRNAs) play an important role in the post-transcriptional regulation of the …

Gene expression profile of HCT-8 cells following single or co-infections with Cryptosporidium parvum and bovine coronavirus

A Jiménez-Meléndez, R Shakya, T Markussen… - Scientific Reports, 2023 - nature.com
Among the causative agents of neonatal diarrhoea in calves, two of the most prevalent are
bovine coronavirus (BCoV) and the intracellular parasite Cryptosporidium parvum. Although …

Persistent Cryptosporidium parvum Infection Leads to the Development of the Tumor Microenvironment in an Experimental Mouse Model: Results of a Microarray …

M Sawant, S Benamrouz-Vanneste, A Mouray… - Microorganisms, 2021 - mdpi.com
Cryptosporidium spp. are enteric protozoa parasites that infect a variety of vertebrate hosts.
These parasites are capable of inducing life-threatening gastrointestinal disease in …

Liposome-based nanocarriers loaded with anthrax lethal factor and armed with anti-CD19 VHH for effectively inhibiting MAPK pathway in B cells

SR Banihashemi, F Rahbarizadeh, AZ Hosseini… - International …, 2021 - Elsevier
Objective One of the vital signaling pathways in cancer development and metastasis is
mitogen-activated protein kinases (MAPKs). Bacillus anthracis Lethal Toxin (LT) is a potent …

Analysis of sheep peripheral blood mononuclear cells in response to Echinococcus granulosus microRNA-71 overexpression

Y Li, L Yan, D Ci, R Li, W Li, T Xia, H Shi, M Ayaz… - Molecular and …, 2023 - Elsevier
Cyst echinococcosis, caused by Echinococcus granulosus, remains a zoonotic disease
posing a great threat to public health and meat production industry. Sheep infected with E …