The circadian clock evolved in diverse organisms to integrate external environmental
changes and internal physiology. The clock endows the host with temporal precision and …

Liver fibrosis is an advanced liver disease condition, which could progress to cirrhosis and
hepatocellular carcinoma. To date, there is no direct approved antifibrotic therapy, and …

Bioinspired out-of-equilibrium systems will set the scene for the next generation of molecular
materials with active, adaptive, autonomous, emergent and intelligent behavior. Indeed life …

Circadian clocks coordinate physiology and behavior with the 24h solar day to provide
temporal homeostasis with the external environment. The molecular clocks that drive these …

In mammals, multiple physiological, metabolic, and behavioral processes are subject to
circadian rhythms, adapting to changing light in the environment. Here we analyzed …

Temporal organization of physiology is critical for human health. In the past, humans
experienced predictable periods of daily light and dark driven by the solar day, which …

It has been established that 4.4 to 20% of the general population suffers from a major
depressive disorder (MDD), which is frequently associated with a dysregulation of normal …

The timing and nutritional composition of food intake are important zeitgebers for the
biological clocks in humans. Thus, eating at an inappropriate time (eg, during the night) may …

The interest in the systematic study of the circadian typology (CT) is relatively recent and has
developed rapidly in the two last decades. All the existing data suggest that this individual …

Circadian rhythms and cellular metabolism are intimately linked. Here, we reveal that a high-
fat diet (HFD) generates a profound reorganization of specific metabolic pathways, leading …