Smoke inhalation injury leads to various acute and chronic lung diseases and thus is the
dominant cause of fire-related fatalities. In a search for an effective treatment and validation …

Opioid-based analgesics provide the mainstay for attenuating burn pain, but they have a
myriad of side effects including respiratory depression, nausea, impaired gastrointestinal …

Background. One of the most plentiful sources for MSCs is the bone marrow; however, it is
unknown whether MSC yield differs among different bone marrow sites. In this study, we …

Mesenchymal stem cells (MSCs) are a promising form of therapy for acute respiratory
distress syndrome (ARDS). The objective of this study was twofold:(a) to characterize …

Background Acute respiratory distress syndrome (ARDS) is multifactorial and can result from
sepsis, trauma, or pneumonia, amongst other primary pathologies. It is one of the major …

BACKGROUND: Current respiratory monitoring technologies such as pulse oximetry and
capnography have been insufficient to identify early signs of respiratory compromise in …

Background Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) is a lethal
disease with limited therapeutic options and an unacceptably high mortality rate …

Severe burn results in systemic inflammatory response syndrome (SIRS) and multiple organ
dysfunction (MOD). Currently, large-animal models of burn-induced SIRS/MOD mostly use …

Hyper or hypoventilation may have serious clinical consequences in critically ill patients and
should be generally avoided, especially in neurosurgical patients. Therefore, monitoring of …

Background Monitoring respiratory status using end tidal CO2 (EtCO2), which reliably
reflects arterial PaCO2 in intubated patients under general anesthesia, has often proven …