Autophagy and its role in gastric cancer

Y Cao, Y Luo, J Zou, J Ouyang, Z Cai, X Zeng, H Ling… - Clinica Chimica …, 2019 - Elsevier
Autophagy, which is tightly regulated by a series of autophagy-related genes (ATGs), is a
vital intracellular homeostatic process through which defective proteins and organelles are …

A review of cancer genetics and genomics studies in Africa

SO Rotimi, OA Rotimi, B Salhia - Frontiers in oncology, 2021 - frontiersin.org
Cancer is the second leading cause of death globally and is projected to overtake infectious
disease as the leading cause of mortality in Africa within the next two decades. Cancer is a …

Effect of the LncRNA GAS5-MiR-23a-ATG3 axis in regulating autophagy in patients with breast cancer

J Gu, Y Wang, X Wang, D Zhou… - Cellular Physiology …, 2018 - search.proquest.com
Background/Aims: An increasing body of evidence shows that long noncoding RNAs
(lncRNAs) are involved in many different cancers. In this study, we aimed to investigate the …

Circular RNA 0007255 regulates the progression of breast cancer through miR‐335‐5p/SIX2 axis

Q Jia, L Ye, S Xu, H Xiao, S Xu, Z Shi, J Li… - Thoracic …, 2020 - Wiley Online Library
Background Breast cancer (BC) is a common cancer in women worldwide. Emerging
evidence has indicated that circular RNA hsa‐circ_0007255 (circ_0007255) is a prognostic …

[HTML][HTML] Development of a novel autophagy-related prognostic signature for serous ovarian cancer

Y An, F Bi, Y You, X Liu, Q Yang - Journal of Cancer, 2018 - ncbi.nlm.nih.gov
Purpose: Considerable evidence suggests that autophagy plays a crucial role in the
biological processes of ovarian cancer. The aim of this study was to develop a novel …

Circ‐PRMT5 promotes breast cancer by the miR‐509‐3p/TCF7L2 axis activating the PI3K/AKT pathway

D Wu, H Jia, Z Zhang, S Li - The Journal of Gene Medicine, 2021 - Wiley Online Library
Background Breast cancer is the most prevalent malignancy occurring in females. In recent
years, emerging evidence has suggested that circular RNAs are involved in the …

The Landscape of BRCA Mutations among Egyptian Women with Breast Cancer

HA Azim, SA Loutfy, HA Azim Jr, NS Kamal… - Oncology and …, 2023 - Springer
Background Deleterious germline mutations in BRCA1 and BRCA2 genes are associated
with a high risk of breast and ovarian cancer. In many developing countries, including Egypt …

Effects of endoplasmic reticulum stress on the autophagy, apoptosis, and chemotherapy resistance of human breast cancer cells by regulating the PI3K/AKT/mTOR …

JT Zhong, J Yu, HJ Wang, Y Shi, TS Zhao… - Tumor …, 2017 - journals.sagepub.com
Nowadays, although chemotherapy is an established therapy for breast cancer, the
molecular mechanisms of chemotherapy resistance in breast cancer remain poorly …

MicroRNA-9 promotes the proliferation, migration, and invasion of breast cancer cells via down-regulating FOXO1

DZ Liu, B Chang, XD Li, QH Zhang, YH Zou - Clinical and Translational …, 2017 - Springer
Purpose The objective of the study was to investigate the role of microRNA-9 (miR-9)
targeting forkhead box O1 (FOXO1) in the proliferation, migration, and invasion of breast …

Genomics in Egypt: current status and future aspects

EA El-Attar, RM Helmy Elkaffas, SA Aglan… - Frontiers in …, 2022 - frontiersin.org
Egypt is the third most densely inhabited African country. Due to the economic burden and
healthcare costs of overpopulation, genomic and genetic testing is a huge challenge …