Lung cancer is one of the most common cancers worldwide and a leading cause of cancer-
related deaths. Macrophages play a key role in the immune response and the tumour …

With the advent of adoptive cellular therapy, chimeric antigen receptor (CAR)-T cell therapy
has gained widespread application in cancer treatment and has demonstrated significant …

The intervertebral disc (IVD) aids in motion and acts to absorb energy transmitted to the
spine. With little inherent regenerative capacity, degeneration of the intervertebral disc …

Tumor-associated macrophages (TAMs) are integral to the tumor microenvironment (TME),
influencing cancer progression significantly. Attracted by cancer cell signals, TAMs exhibit …

Colorectal cancer (CRC) represents a significant global health burden, with high incidence
and mortality rates worldwide. Recent progress in research highlights the distinct clinical …

The colony-stimulating factor 1 receptor (CSF-1R) plays a pivotal role in orchestrating
cellular interactions within the tumor microenvironment (TME). Although the CSF-1R has …

Tumor-associated macrophages (TAMs) are present in the tumor microenvironment and can
polarize into subtypes with different functions and characteristics in response to different …

Antibiotics had proved to be a godsend for mankind since their discovery. They were once
the magical solution to the vexing problem of infection-related deaths. German scientist Paul …

Immunometabolism has been unveiled in the last decade to play a major role in controlling
macrophage metabolism and inflammation. There has been a constant effort to understand …

Macrophage polarization is decisive for homeostasis maintenance and tissue repair. Anti-
inflammatory properties of curcumin (CUR) have been demonstrated in several studies. It …