NKT cells in immunoregulation of tumor immunity: a new immunoregulatory axis

M Terabe, JA Berzofsky - Trends in immunology, 2007 - cell.com
CD1d-restricted natural killer T (NKT) cells have at least two subsets: type I, semi-invariant
TCRα chain-expressing (Vα14Jα18 in mice, Vα24Jα18 in humans), and type II, variable …

NKT cells in tumor immunity: opposing subsets define a new immunoregulatory axis

JA Berzofsky, M Terabe - The Journal of Immunology, 2008 - journals.aai.org
NKT cells are true Ag-specific T cells that also have innate properties and form a bridge
between the innate and adaptive immune systems. Distinct NKT cell subsets play positive …

[HTML][HTML] A digital health platform for assisting the diagnosis and monitoring of COVID-19 progression: An adjuvant approach for augmenting the antiviral response and …

Y Ishay, A Potruch, A Schwartz, M Berg, K Jamil… - Biomedicine & …, 2021 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19), which is a respiratory illness associated
with high mortality, has been classified as a pandemic. The major obstacles for the clinicians …

β-Glycosphingolipids as mediators of both inflammation and immune tolerance: a manifestation of randomness in biological systems

Y Ilan - Frontiers in Immunology, 2019 - frontiersin.org
Plasticity in biological systems is attributed to the combination of multiple parameters which
determine function. These include genotypic, phenotypic, and environmental factors. While …

[HTML][HTML] The role of microtubules in the immune system and as potential targets for gut-based immunotherapy

T Ilan-Ber, Y Ilan - Molecular immunology, 2019 - Elsevier
Microtubules (MTs) are tubular polymers of tubulin that are highly dynamic and found
throughout the cytoplasm. MTs are involved in maintaining cell structure and, together with …

Personalized inherent randomness of the immune system is manifested by an individualized response to immune triggers and immunomodulatory therapies: a novel …

M El-Haj, D Kanovitch, Y Ilan - Immunologic Research, 2019 - Springer
The considerable variability of responses amongst subjects to disease triggers and
immunotherapies is a major obstacle to designing better immune-based therapies …

The contrasting roles of NKT cells in tumor immunity

JA Berzofsky, M Terabe - Current molecular medicine, 2009 - ingentaconnect.com
NKT cells are true T cells that serve as a bridge between the innate and adaptive immune
system, acting as first responders. They recognize lipid antigens rather than peptides, and …

Larger number of invariant natural killer T cells in PBSC allografts correlates with improved GVHD-free and progression-free survival

F Malard, M Labopin, P Chevallier… - Blood, The Journal …, 2016 - ashpublications.org
We studied the impact of a set of immune cells contained within granulocyte colony-
stimulating factor–mobilized peripheral blood stem cell grafts (naïve and memory T-cell …

Liver involvement in Gaucher disease–Review and clinical approach

T Adar, Y Ilan, D Elstein, A Zimran - Blood Cells, Molecules, and Diseases, 2018 - Elsevier
Gaucher disease (GD), one of the most prevalent lysosomal storage diseases, is associated
with glucocerebroside accumulation in cells of the monocyte-macrophage system in various …

Influence of post-transplant mucosal-associated invariant T cell recovery on the development of acute graft-versus-host disease in allogeneic bone marrow …

K Kawaguchi, K Umeda, E Hiejima, A Iwai… - International journal of …, 2018 - Springer
Mucosal-associated invariant T (MAIT) and invariant natural killer T (iNKT) cells are T cell
subpopulations that possess innate-like properties. We examined the impact of post …