Probably the most familiar and intensively studied property of synthetic opioids and their
naturally occurring counterparts, the endogenous opioid peptides (endorphins), is their …

The third edition of this monograph continues to have the goal of providing an overview of
current thought about the spinal cord mechanisms that are responsible for sensory …

The substantia gelatinosa Rolandi (SGR) was first described about two centuries ago. In the
following decades an enormous amount of information has permitted us to understand-at …

Highly selective tritiated ligands and quantitative autoradiography have been used to study
μ, δ and κ binding sites in the dorsal horn of the rat spinal cord. We have measured the …

Erfahren Sie alles über Opioide, was Sie schon immer wissen wollten:-Physiologie des
Schmerzgeschehens,-Wirkungsweise, Nebenwirkungen von Opioiden,-Indikationen und …

Inoculation of the right hind paw with Mycobacterium butyricum rapidly led to swelling and
inflammation. The afflicted limb showed an enhanced sensitivity to noxious pressure …

It has been suggested that the opioid dynorphin, an endogenous agonist for k‐opiate
receptors, contributes to secondary tissue damage after spinal cord injury. To evaluate this …

In man, heterotopic painful thermal conditioning stimuli induce parallel decreases in the
spinal nociceptive flexion (R III) reflex and the concurrent sensation of pain elicited by …

Dynorphin dose-dependently increased the tail flick latency of rats to radiant heat following
its intrathecal injection. This effect was accompanied by an alteration in motor function that …

The purpose of this study was to use [3 H] DAMGO,[3 H] DTLET and [3 H] EKC in the
presence of 100 nM DAMGO and 100 nM DTLET, combined with a quantitative …