Facts and recommendations about total homocysteine determinations: an expert opinion

H Refsum, AD Smith, PM Ueland, E Nexo… - Clinical …, 2004 - academic.oup.com
Background: Measurement of plasma total homocysteine has become common as new
methods have been introduced. A wide range of disorders are associated with increased …

Homocysteine and vascular disease

GJ Hankey, JW Eikelboom - The lancet, 1999 - thelancet.com
For more than 20 years, moderately raised concentrations of total homocysteine (tHcy) have
been associated with an increased risk of atherothrombotic vascular events but only recently …

Homocysteine and cardiovascular disease: evidence on causality from a meta-analysis

DS Wald, M Law, JK Morris - Bmj, 2002 - bmj.com
Objective: To assess whether the association of serum homocysteine concentration with
ischaemic heart disease, deep vein thrombosis and pulmonary embolism, and stroke is …

Homocysteine and risk of ischemic heart disease and stroke: a meta-analysis

Homocysteine Studies Collaboration… - Jama, 2002 - jamanetwork.com
ContextIt has been suggested that total blood homocysteine concentrations are associated
with the risk of ischemic heart disease (IHD) and stroke. ObjectiveTo assess the relationship …

Antioxidants and disease: more questions than answers

NJ Temple - Nutrition research, 2000 - Elsevier
Reactive oxygen species are widely believed to be involved in the etiology of many
diseases as indicated by the signs of oxidative stress seen in those diseases. Conversely …

Efficacy of folic acid supplementation in stroke prevention: a meta-analysis

X Wang, X Qin, H Demirtas, J Li, G Mao, Y Huo, N Sun… - The Lancet, 2007 - thelancet.com
Background The efficacy of treatments that lower homocysteine concentrations in reducing
the risk of cardiovascular disease remains controversial. Our aim was to do a meta-analysis …

Homocyst (e) ine, diet, and cardiovascular diseases: a statement for healthcare professionals from the Nutrition Committee, American Heart Association

MR Malinow, AG Bostom, RM Krauss - Circulation, 1999 - Am Heart Assoc
ported to have higher geometric mean fasting homocyst (e) ine levels than C/T
heterozygotes or C/C homozygotes when folate status was below the population median …

Homocyst (e) ine and cardiovascular disease: a critical review of the epidemiologic evidence

JW Eikelboom, E Lonn, J Genest Jr… - Annals of internal …, 1999 - acpjournals.org
Purpose: To review epidemiologic studies on the association between homocyst (e) ine
level and risk for cardiovascular disease and the potential benefits of homocysteine …

[HTML][HTML] The Hordaland Homocysteine Study: a community-based study of homocysteine, its determinants, and associations with disease

H Refsum, E Nurk, AD Smith, PM Ueland… - The Journal of …, 2006 - Elsevier
ABSTRACT The Hordaland Homocysteine Study (HHS) is a population-based study of more
than 18,000 men and women in the county of Hordaland in Western Norway. The first …

Homocysteine level and coronary heart disease incidence: a systematic review and meta-analysis

LL Humphrey, R Fu, K Rogers, M Freeman… - Mayo Clinic …, 2008 - Elsevier
OBJECTIVE To determine whether an elevated homocysteine level is an independent risk
factor for the development of coronary heart disease (CHD) to aid the US Preventive …