Current hydrogel advances in physicochemical and biological response-driven biomedical application diversity

H Cao, L Duan, Y Zhang, J Cao, K Zhang - Signal transduction and …, 2021 - nature.com
Hydrogel is a type of versatile platform with various biomedical applications after rational
structure and functional design that leverages on material engineering to modulate its …

Recent advances in injectable hydrogels for controlled and local drug delivery

F Rizzo, NS Kehr - Advanced healthcare materials, 2021 - Wiley Online Library
Injectable hydrogels have received considerable interest in the biomedical field due to their
potential applications in minimally invasive local drug delivery, more precise implantation …

Poly(N-isopropylacrylamide)-Based Hydrogels for Biomedical Applications: A Review of the State-of-the-Art

MJ Ansari, RR Rajendran, S Mohanto, U Agarwal… - Gels, 2022 - mdpi.com
A prominent research topic in contemporary advanced functional materials science is the
production of smart materials based on polymers that may independently adjust their …

Recent advances in thermo-sensitive hydrogels for drug delivery

Y Yu, Y Cheng, J Tong, L Zhang, Y Wei… - Journal of Materials …, 2021 - pubs.rsc.org
Hydrogels are cross-linked hydrophilic macromolecules that contain a certain amount of
water. Due to their biocompatible, highly tunable and hydrophilic nature, hydrogels have …

Thermo-responsive polymers: Applications of smart materials in drug delivery and tissue engineering

M Sponchioni, UC Palmiero, D Moscatelli - Materials Science and …, 2019 - Elsevier
Synthetic polymers are attracting great attention in the last decades for their use in the
biomedical field as nanovectors for controlled drug delivery, hydrogels and scaffolds …

Polymeric systems for bioprinting

ML Bedell, AM Navara, Y Du, S Zhang… - Chemical …, 2020 - ACS Publications
Bioprinting is rapidly being adopted as a major method for fabricating tissue engineering
constructs. Through the precise deposition of cell-and bioactive molecule-laden materials …

Recent advances on reactive oxygen species-responsive delivery and diagnosis system

H Ye, Y Zhou, X Liu, Y Chen, S Duan, R Zhu… - …, 2019 - ACS Publications
Reactive oxygen species (ROS) play crucial roles in biological metabolism and intercellular
signaling. However, ROS level is dramatically elevated due to abnormal metabolism during …

[HTML][HTML] A BRD4 PROTAC nanodrug for glioma therapy via the intervention of tumor cells proliferation, apoptosis and M2 macrophages polarization

T Yang, Y Hu, J Miao, J Chen, J Liu, Y Cheng… - … Pharmaceutica Sinica B, 2022 - Elsevier
Glioma is a primary aggressive brain tumor with high recurrence rate. The poor efficiency of
chemotherapeutic drugs crossing the blood‒brain barrier (BBB) is well-known as one of the …

Extravascular gelation shrinkage-derived internal stress enables tumor starvation therapy with suppressed metastasis and recurrence

K Zhang, Y Fang, Y He, H Yin, X Guan, Y Pu… - Nature …, 2019 - nature.com
Despite the efficacy of current starvation therapies, they are often associated with some
intrinsic drawbacks such as poor persistence, facile tumor metastasis and recurrence …

Reactive oxygen species–degradable polythioketal urethane foam dressings to promote porcine skin wound repair

P Patil, KA Russo, JT McCune, AC Pollins… - Science translational …, 2022 - science.org
Porous, resorbable biomaterials can serve as temporary scaffolds that support cell
infiltration, tissue formation, and remodeling of nonhealing skin wounds. Synthetic …