The thymus gland is a central lymphoid organ in which bone marrow-derived T cell
precursors undergo differentiation, eventually leading to migration of positively selected …

Infectious disease immunology has largely focused on the effector immune response,
changes in the blood and peripheral lymphoid organs of infected individuals, and vaccine …

Cell migration is crucial for thymocyte differentiation, and the cellular interactions involved
now begin to be unraveled, with chemokines, extracellular matrix (ECM) proteins, and their …

GH has been shown to modulate various functions of the thymus. We now demonstrate the
production of human GH (hGH) by human thymic cells, and the expression of GH receptors …

Genes encoding the five Atlantic halibut (Hippoglossus hippoglossus L.) cytokines;
interleukin (IL)-1β, IL-6, IL-11b, IL-12βc, and interferon (IFN) γ, were cloned and …

In the periphery, IL-18 synergistically induces the expression of the Th1 cytokine IFN-γ in the
presence of IL-12 and the Th2 cytokines IL-5 and IL-13 in the presence of IL-2. Although the …

Intrathymic T-cell differentiation is a key process for the development and maintenance of
cell-mediated immunity, and occurs concomitantly to highly regulated migratory events. We …

Cell adhesion, migration, differentiation and survival or death is amongst a large spectrum of
biological responses that can be elicited by ligation of extracellular matrix components to …

Background The thymus is a central lymphoid organ, in which bone marrow-derived T cell
precursors undergo a complex process of maturation. Developing thymocytes interact with …

Cyclosporin A (CSA)-induced autologous graft-vs-host disease (autoGVHD) is an
autoimmune syndrome initiated by autoeffector T cells presumed to be exported from the …