Activated neutrophils release neutrophil extracellular traps (NETs) in response to a variety of
stimuli. NETosis is driven by protein-arginine deiminase type 4, with the release of …

Abstract Coronavirus disease 2019 (Covid-19) is a worldwide infectious disease caused by
severe acute respiratory coronavirus 2 (SARS-CoV-2). In severe SARS-CoV-2 infection …

The transcription factor NF-κB is a central mediator of inflammation with multiple links to
thrombotic processes. In this review, we focus on the role of NF-κB signaling in cell types …

The contributions by blood cells to pathological venous thrombosis were only recently
appreciated. Both platelets and neutrophils are now recognized as crucial for thrombus …

This review will briefly outline the major signaling pathways in PMA-activated neutrophils.
PMA is widely used to understand neutrophil pathways and formation of NETs. PMA …

Objective Antiphospholipid antibodies (aPL), especially those targeting β2‐glycoprotein I
(β2GPI), are well known to activate endothelial cells, monocytes, and platelets, with …

In this paper, a model is proposed of the pathophysiological processes of COVID-19 starting
from the infection of human type II alveolar epithelial cells (pneumocytes) by SARS-CoV-2 …

The formation of neutrophil extracellular traps (NETs), known as NETosis, was first observed
as a novel immune response to bacterial infection, but has since been found to occur …

Two metal-free explosives, tetrazolo [1, 5-b] pyridazine-containing molecules [6-azido-8-
nitrotetrazolo [1, 5-b] pyridazine-7-amine (3at) and 8-nitrotetrazolo [1, 5-b] pyridazine-6, 7 …

Following strong activation signals, several types of immune cells reportedly release
chromatin and granular proteins into the extracellular space, forming DNA traps. This …