Therapeutic drug monitoring (TDM) and model‐informed precision dosing (MIPD) have
evolved as important tools to inform rational dosing of antibiotics in individual patients with …

Linezolid is an antibiotic used to treat infections caused by drug-resistant gram-positive
organisms, including vancomycin-resistant Enterococcus faecium, multi-drug resistant …

In recent years, many studies on population pharmacokinetics of linezolid have been
conducted. This comprehensive review aimed to summarize population pharmacokinetic …

Introduction Linezolid can cause serious adverse effects including thrombocytopenia and
anemia. Here, we focus specifically on linezolid-related hematological toxicity in adult …

Linezolid is an oxazolidinone antibacterial drug, and its therapeutic drug monitoring and
individualized treatment have been challenged since its approval. With the in-depth clinical …

Linezolid is the first synthetic oxazolidone agent to treat infections caused by Gram-positive
pathogens. Infected patients with liver dysfunction (LD) are more likely to suffer from adverse …

Background: Linezolid is associated with myelosuppression, which may cause failure in
optimally treating bacterial infections. The study aimed to define the pharmacokinetic …

Aim This study investigates the pharmacokinetic/pharmacodynamic (PK/PD) target
attainment of linezolid in patients infected with multidrug‐resistant (MDR) tuberculosis (TB) …

Aims Linezolid is often used for the infections caused by drug‐resistant Gram‐positive
bacteria. Recent studies suggest that large between‐subject variability (BSV) and within …

Introduction Linezolid is an antimicrobial with broad activity against Gram-positive bacteria.
Thrombocytopenia is one of its most common side effects often leading to severe …