Proteomic Profiling of Small-Cell Lung Cancer: A Systematic Review

AM Elshoeibi, B Elsayed, MZ Kaleem, MR Elhadary… - Cancers, 2023 - mdpi.com
Simple Summary Our study centers on refining the diagnosis of small-cell lung cancer
(SCLC), a unique subtype with distinct therapeutic implications compared to other lung …

Down-regulation of PADI2 prevents proliferation and epithelial-mesenchymal transition in ovarian cancer through inhibiting JAK2/STAT3 pathway in vitro and in vivo …

L Liu, Z Zhang, G Zhang, T Wang, Y Ma… - Journal of translational …, 2020 - Springer
Background Epithelial ovarian cancer (EOC) is the most lethal disease among female
genital malignant tumors. Peptidylarginine deiminase type II (PADI II) has been shown to …

Identification of novel PAD2 inhibitors using pharmacophore-based virtual screening, molecular docking, and MD simulation studies

P Jha, P Rajoria, P Poonia, M Chopra - Scientific Reports, 2024 - nature.com
In the realm of epigenetic regulation, Protein arginine deiminase 2 (PAD2) stands out as a
therapeutic target due to its significant role in neurological disorders, rheumatoid arthritis …

Involvement of m6A regulatory factor IGF2BP1 in malignant transformation of human bronchial epithelial Beas-2B cells induced by tobacco carcinogen NNK

J Zhou, R Xiong, J Zhou, X Guan, G Jiang… - Toxicology and Applied …, 2022 - Elsevier
Abstract Nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) is a Group 1
human carcinogen, as classified by the International Agency for Research of Cancer (IARC) …