TET1 regulates gene expression and repression of endogenous retroviruses independent of DNA demethylation
P Stolz, AS Mantero, A Tvardovskiy, E Ugur… - Nucleic Acids …, 2022 - academic.oup.com
Abstract DNA methylation (5-methylcytosine (5mC)) is critical for genome stability and
transcriptional regulation in mammals. The discovery that ten-eleven translocation (TET) …
transcriptional regulation in mammals. The discovery that ten-eleven translocation (TET) …
[HTML][HTML] Polycomb repressive complex 2 shields naïve human pluripotent cells from trophectoderm differentiation
B Kumar, C Navarro, N Winblad, JP Schell, C Zhao… - Nature Cell …, 2022 - nature.com
The first lineage choice in human embryo development separates trophectoderm from the
inner cell mass. Naïve human embryonic stem cells are derived from the inner cell mass and …
inner cell mass. Naïve human embryonic stem cells are derived from the inner cell mass and …
[图书][B] Quantitative Methods for Profiling Dynamic Chromatin Features
B Kumar - 2022 - search.proquest.com
Living systems, from entire organisms down to the single cells constituting them aredynamic
entities that continuously adapt and respond to their local environment. Cellsachieve this …
entities that continuously adapt and respond to their local environment. Cellsachieve this …