Integrating imaging and omics data: a review

L Antonelli, MR Guarracino, L Maddalena… - … Signal Processing and …, 2019 - Elsevier
We refer to omics imaging as an emerging interdisciplinary field concerned with the
integration of data collected from biomedical images and omics analyses. Bringing together …

Pathology and hippocampal atrophy in Alzheimer's disease

G Halliday - The Lancet Neurology, 2017 - thelancet.com
Over time, reduced hippocampal volume results in an amnestic syndrome, a core feature of
Alzheimer's disease. 1 Damage to the hippocampus is incorporated into the pathological …

A three-stage, deep learning, ensemble approach for prognosis in patients with Parkinson's disease

KH Leung, SP Rowe, MG Pomper, Y Du - EJNMMI research, 2021 - Springer
Abstract Background Diagnosis of Parkinson's disease (PD) is informed by the presence of
progressive motor and non-motor symptoms and by imaging dopamine transporter with [123 …

Combining neuroimaging and omics datasets for disease classification using graph neural networks

YH Chan, C Wang, WK Soh… - Frontiers in Neuroscience, 2022 - frontiersin.org
Both neuroimaging and genomics datasets are often gathered for the detection of
neurodegenerative diseases. Huge dimensionalities of neuroimaging data as well as omics …

Joint-connectivity-based sparse canonical correlation analysis of imaging genetics for detecting biomarkers of Parkinson's disease

M Kim, JH Won, J Youn, H Park - IEEE transactions on medical …, 2019 - ieeexplore.ieee.org
Imaging genetics is a method used to detect associations between imaging and genetic
variables. Some researchers have used sparse canonical correlation analysis (SCCA) for …

Integration of multimodal data

M Lorenzi, M Deprez, I Balelli, AL Aguila… - Machine Learning for …, 2023 - Springer
This chapter focuses on the joint modeling of heterogeneous information, such as imaging,
clinical, and biological data. This kind of problem requires to generalize classical uni-and …

Predictive modelling of Parkinson's disease progression based on RNA-Sequence with densely connected deep recurrent neural networks

S Ahmed, M Komeili, J Park - Scientific Reports, 2022 - nature.com
The advent of recent high throughput sequencing technologies resulted in unexplored big
data of genomics and transcriptomics that might help to answer various research questions …

Structure-constrained combination-based nonlinear association analysis between incomplete multimodal imaging and genetic data for biomarker detection of …

X Chen, T Wang, H Lai, X Zhang, Q Feng… - Medical Image Analysis, 2022 - Elsevier
Multimodal imaging data are widely applied in imaging genetic studies to identify
associations between imaging and genetic data for the biomarker detection of …

Parkinson's Disease Risk Variant rs9638616 is Non-Specifically Associated with Altered Brain Structure and Function

T Welton, TWJ Teo, LL Chan, EK Tan… - Journal of Parkinson's …, 2024 - content.iospress.com
Background: A genome-wide association study (GWAS) variant associated with Parkinson's
disease (PD) risk in Asians, rs9638616, was recently reported, and maps to …

Bridging Imaging and Clinical Scores in Parkinson's Progression Via Multimodal Self-Supervised Deep Learning.

FJ Martinez-Murcia, JE Arco… - … Journal of Neural …, 2024 - europepmc.org
Neurodegenerative diseases pose a formidable challenge to medical research, demanding
a nuanced understanding of their progressive nature. In this regard, latent generative …