Heart failure is a major health risk, and with limited availability of donor organs, there is an
increasing need for developing cardiac assist devices (CADs). Mock circulatory loops (MCL) …

Abstract β-carotene (BC), a lipid-soluble tetraterpene precursor to vitamin A, widely
distributed in plants, including many used in human diet, has well-known health-enhancing …

Background Continuous-flow left ventricular assist devices (LVADs) cause blood trauma that
includes von Willebrand factor degradation, platelet activation, and subclinical hemolysis …

Introduction: The design of implantable blood pumps is either based on displacement
pumps with membranes or rotary pumps. Both pump types have limitations to meet the …

This article provides an overview of the design challenges associated with scaling the low-
shear pulsatile TORVAD ventricular assist device (VAD) for treating pediatric heart failure. A …

This paper presents an approach for real-time estimation of the systemic vascular resistance
(SVR) of heart failure patients who have a left ventricular assist device (LVAD). Notably, an …

BACKGROUND Survival with advanced heart failure remains poor. Cardiac transplantation
offers the best opportunity for long-term survival. However, limited availability of donor …

Abstract Our new Virtual Mock Loop (VML) is a mathematical model designed to simulate
the human cardiovascular system and gauge performance of mechanical circulatory support …

Background With the increasing use of mechanical circulatory support for long-term
augmentation of cardiopulmonary function, the need for safer devices is apparent. Pump …

The two-piston toroidal pump (2PTP) is a new pulsatile pumping paradigm with potential
physiological advantages compared to existing continuous flow blood pump technologies …