Stroke is a devastating disease with high morbidity and mortality. Animal models are
indispensable tools that can mimic stroke processes and can be used for investigating …

Ischemic stroke affects over 77 million people annually around the globe. Due to the
blockage of a blood vessel caused by a stroke, brain tissue becomes ischemic. While …

The neuroprotective effect and mechanism of the flavonoid-rich extract (FRE) from Rosa
laevigata Michx fruit on cerebral ischemia–reperfusion (I/R) injury were investigated. The …

Ischemic cerebral stroke is one of the leading causes of death and disability in humans.
However, molecular processes underlying the development of this pathology remain poorly …

The emerging second near-infrared (NIR-II) fluorescence imaging has shown great promise
for in vivo imaging of small animals such as mice, yet the onward movement to large-size …

Apigenin is a natural flavonoid found in several dietary plant foods as vegetables and fruits.
To investigate potential anti‐ischemia/reperfusion injury properties of apigenin in vitro, cell …

Kv2. 1 channels mediate cell death–enabling loss of cytosolic potassium in neurons
following plasma membrane insertion at somatodendritic clusters. Overexpression of the …

The middle cerebral artery occlusion (MCAO) model in rats closely imitates ischemic stroke
and is widely used. Existing instrumental methods provide a certain level of MCAO …

Human ischemic stroke is very complex, and no single preclinical model can comprise all
the variables known to contribute to stroke injury and recovery. Hypertension, diabetes, and …

NMDA receptor (NMDAR) is known for its ionotropic function. But recent evidence suggests
that NMDAR also has a non-ionotropic property. To determine the role of non-ionotropic …