Neurotransmitters are considered as a fundamental regulator in the process of neuronal
growth, differentiation and survival. Parkinson's Disease (PD) occurs due to extensive …

Abstract γ-Aminobutyric acid (GABA) transporter 1 (GAT1) regulates neuronal excitation of
the central nervous system by clearing the synaptic cleft of the inhibitory neurotransmitter …

Abstract γ-Aminobutyric acid (GABA), an important inhibitory neurotransmitter in the central
nervous system, is recycled through specific GABA transporters (GATs). GAT1, which is …

Dysregulation of excitatory and inhibitory signaling is commonly observed in major
psychiatric disorders, including schizophrenia, depression, and bipolar disorder, and is often …

Recent studies show that neuron-glial communication plays an important role in
neurological diseases. Particularly, dysfunction of astroglial glutamate transporter GLT-1 has …

Despite extensive research in recent decades, knowledge of the pathophysiology of
depression in neural circuits remains limited. Recently, the lateral habenula (LHb) has been …

Although the output of the lateral habenula (LHb) controls the activity of midbrain
dopaminergic and serotonergic systems, which are implicated in the pathophysiology of …

Objective The aim of the present study was to investigate whether serotonin1B (5-HT1B)
receptor-adenylate cyclase (AC)-protein kinase A (PKA) signal pathway in the lateral …

Gut microbiota can regulate host brain functions and influence various physiological and
pathological processes through the brain–gut axis. To systematically elucidate the …

Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the central
nervous system (CNS). Most GABAergic neurons synthesize GABA from glutamate and …