The diversity of chemicals complicates the question of their exposure and risk to humans
and biota. It is also becoming harder to detect and accurately understand complex …

The transfer of neutral compounds between immiscible phases in chromatographic or
environmental systems can be described by six solute properties (solute descriptors) using …

Revised descriptors for 74 varied compounds recommended for the characterization of
reversed-phase silica columns using the solvation parameter model are assigned by the …

Fast and accurate estimation of lipophilicity for organofluorine molecules is in great demand
for accelerating drug and materials discovery. A lipophilicity data set of organofluorine …

Derivatization, or chemical structure modification, is often used in bioanalysis performed by
liquid chromatography technique in order to enhance detectability or to improve the …

The solvent strength parameter (slope) and intercept (log kw) of the linear solvent strength
model are determined for methanol-water (17 columns), acetonitrile-water (15 columns) …

Biopartitioning processes are challenging to study and often require the sacrifice of multiple
animals. Therefore, it is more practical and cost-effective to correlate these processes with …

Except for alkanes, most organic compounds are hydrogen-bond bases. The B° descriptor of
the solvation parameter model provides a convenient measure of the effective (or …

The distribution of neutral compounds in biphasic separation systems can be described by
the solvation parameter model using six solute properties, or descriptors. These descriptors …

The solvation parameter model uses five system independent descriptors to characterize
compound properties defined as excess molar refraction, E, dipolarity/polarizability, S …