Opinion statement Melanoma is one of the deadliest malignancies. Its incidence has been
significantly increasing in most countries in recent decades. Acral melanoma (AM), a …

This study highlights aspects of the latest clinical research conducted on the relationship
between immune checkpoints and tumor metastasis. The overview of each immune …

Objective To investigate the ferroptosis-related long non-coding RNAs (FRLncs) implicated
in influencing the prognostic and immune microenvironment in osteosarcoma (OS), and to …

Costimulatory molecules have been proven to enhance antitumor immune responses, but
their roles in clear cell renal cell carcinoma (ccRCC) remain unexplored. In this study, we …

Objective. Autophagy and long noncoding RNAs (lncRNAs) have been the focus of research
on the pathogenesis of melanoma. However, the autophagy network of lncRNAs in …

Background OX40 and OX40 ligand (OX40L), as essential immune checkpoint (IC)
modulators, are highly correlated with cancer immunity regulation as well as tumor …

Early identification of gastric cancer (GC) is associated with a superior survival rate
compared to advanced GC. However, the poor specificity and sensitivity of traditional …

Abstract Although PD-1 and CTLA-4 inhibitors have proven successful in a range of
malignancies, there are subsets of patients that do not respond to these agents due to …

Melanoma is an extremely malignant tumor with early metastasis and high mortality. Little is
known about the process of by which melanoma occurs, as its mechanism is very complex …

Ferroptosis plays an important role in cancer. However, studies about ferroptosis-related
lncRNAs (FRLs) in skin cutaneous melanoma (SKCM) are scarce. Moreover, the …