Ion channels play a central role in the regulation of nearly every cellular process. Dating
back to the classic 1952 Hodgkin–Huxley model of the generation of the action potential, ion …

PART I THE ENDOTHELIUM has long been viewed as an inert cellophane-like membrane
that lines the circulatory system with its primary essential function being the maintenance of …

Since the first description of hydrogen sulfide (H2S) as a toxic gas in 1713 by Bernardino
Ramazzini, most studies on H2S have concentrated on its toxicity. In 1989, Warenycia et al …

In arteries, muscarinic agonists such as acetylcholine release an unidentified, endothelium-
derived hyperpolarizing factor (EDHF) which is neither prostacyclin nor nitric oxide,,. Here …

Endothelium‐dependent hyperpolarizing factor (EDHF) is a powerful vasodilator influence in
small resistance arteries and thus an important modulator of blood pressure and flow. As the …

Faraci, Frank M., and Donald D. Heistad. Regulation of the Cerebral Circulation: Role of
Endothelium and Potassium Channels. Physiol. Rev. 78: 53–97, 1998.—Several new …

The properties and roles of ATP-sensitive (KATP) and inwardly rectifying (KIR) potassium
channels are reviewed. Potassium channels regulate the membrane potential of smooth …

This review focuses on the effects of thyroid hormones in vascular and renal systems.
Special emphasis is given to the mechanisms by which thyroid hormones affect the …

The transient receptor potential (TRP) superfamily consists of a large number of
nonselective cation channels with variable degree of Ca2+-permeability. The 28 mammalian …

This book represents the first serious attempt to explain the fundamental basis of
ozonetherapy and is a relevant step towards achieving further progress. Ozone is now …