Ischemia/reperfusion injury (IRI) permeates a variety of diseases and is a ubiquitous
concern in every transplantation proceeding, from whole organs to modest grafts. Given its …

The master pro-inflammatory cytokine, tumour necrosis factor (TNF), has been shown to
modulate multiple signalling pathways, with wide-ranging downstream effects. TNF plays a …

Abstract Tumor Necrosis Factor (TNF), initially known for its tumor cytotoxicity, is a potent
mediator of inflammation, as well as many normal physiological functions in homeostasis …

TNF (tumor necrosis factor) is both a pro-inflammatory and anti-inflammatory cytokine that is
central to the development of autoimmune disease, cancer, and protection against infectious …

Tumor necrosis factor-α (TNFα) was cloned over 2 decades ago and its identification in part
led to the discovery of a super family of tumor necrosis factors (TNFs) and their receptors …

Tumor necrosis factor-α (TNF-α) has been shown to have certain catabolic effects on fat cells
and whole animals. An induction of TNF-α messenger RNA expression was observed in …

Breast cancer is the most frequently diagnosed cancer and the principal cause of mortality
by malignancy in women and represents a main problem for public health worldwide. Tumor …

Cutaneous melanin pigment plays a critical role in camouflage, mimicry, social
communication, and protection against harmful effects of solar radiation. Melanogenesis is …

APO‐1 (Fas/CD95), a member of the tumor necrosis factor receptor superfamily, induces
apoptosis upon receptor oligomerization. In a search to identify intracellular signaling …

Many diverse activities of tumor necrosis factor (TNF) are signaled through TNF receptor 1
(TNFRl). We have identified a novel 34 kDa protein, designated TRADD, that specifically …