Almost half of all preterm births are caused or triggered by an inflammatory process at the
feto-maternal interface resulting in preterm labor or rupture of membranes with or without …

The central nervous system (CNS) and the immune system are both intricate and highly
organized systems that regulate the entire body, with both sharing certain common features …

Ubiquitous expression of amyotrophic lateral sclerosis (ALS)-causing mutations in
superoxide dismutase 1 (SOD1) provokes noncell autonomous paralytic disease. By …

Both genetic background and environmental factors, very probably viruses, appear to play a
role in the etiology of multiple sclerosis (MS). Lessons from viral experimental models …

Differentiation of oligodendrocyte progenitor cells requires activation of the Src family kinase
Fyn. The signals that are upstream and downstream of Fyn in oligodendrocytes remain …

There are an estimated 18 million Alzheimer's disease (AD) sufferers worldwide and with no
disease modifying treatment currently available, development of new therapies represents …

Several proteins are expressed in both immune and nervous systems. However, their
putative nonimmune functions in the brain remain poorly understood. KARAP/DAP12 is a …

Fyn is a non-receptor or cytoplasmatic tyrosine kinase (TK) belonging to the Src family
kinases (SFKs) involved in multiple transduction pathways in the central nervous system …

Central nervous system myelination requires the synthesis of large amounts of myelin basic
protein (MBP) at the axon–glia contact site. MBP messenger RNA (mRNA) is transported in …

Immunotherapeutic efforts to slow the clinical progression of Alzheimer's disease (AD) by
lowering brain amyloid-β (Aβ) have included Aβ vaccination, intravenous immunoglobulin …