BACKGROUND: The optimal type of neoadjuvant therapy regimen in rectal cancer is
contentious. OBJECTIVE: This study aimed to review the impact of neoadjuvant therapy on …

The main evidences of epidemiology, diagnostic imaging, pathology, surgery, radiotherapy,
chemotherapy and follow-up are reviewed to optimize the routine treatment of rectal cancer …

Background This study examined the prognostic impact of the circumferential resection
margin (CRM) in patients with rectal cancer treated by total mesorectal excision (TME) with …

Background. The Norwegian Rectal Cancer Project was initated in 1993 with the aims of
improving surgery, decreasing local recurrence rates, improving survival, and establishing a …

Background Circumferential resection margin is considered an important prognostic
parameter after rectal cancer surgery, but its impact might have changed because of …

Introduction Introduction of total mesorectal excision (TME) surgery for rectal cancer
decreased local recurrence dramatically. Additional neoadjuvant chemoradiation (nCR) is …

Rectal cancer accounts for one third of all colorectal cancers. The age adjusted death rates
from colorectal cancer have declined over recent decades due to a combination of colorectal …

The ability to predict complete pathologic response or sensitivity to radiation before
treatment would have a significant impact on the selection of patients for preoperative …

Aim Although T3 tumour subclassifications have been linked to prognosis, its mandatory
adoption in histopathological reports has not been incorporated. This article focusses on the …

The management of localized rectal cancer requires a multidisciplinary approach to optimize
outcomes, reduce morbidity and prevent under or overtreatments. While early stages may …