Nutrition for precision health: The time is now

L Qi - Obesity, 2022 - Wiley Online Library
Precision nutrition has emerged as a boiling area of nutrition research, with a particular
focus on revealing the individual variability in response to diets that is determined mainly by …

Investigating the postprandial metabolome after challenge tests to assess metabolic flexibility and dysregulations associated with cardiometabolic diseases

G Lépine, M Tremblay-Franco, S Bouder, L Dimina… - Nutrients, 2022 - mdpi.com
This review focuses on the added value provided by a research strategy applying
metabolomics analyses to assess phenotypic flexibility in response to different nutritional …

Postprandial metabolism is impaired in overweight normoglycemic young adults without family history of diabetes

AA Kumar, G Satheesh, G Vijayakumar, M Chandran… - Scientific Reports, 2020 - nature.com
While the risk factors for Type 2 diabetes (T2DM) are known, early predictive markers of
transition from normal to a prediabetes state are unidentified. We studied the basal …

Lipidomics in diabetes

EJ Kim, R Ramachandran… - Current Opinion in …, 2022 - journals.lww.com
Lipidomics in diabetes : Current Opinion in Endocrinology, Diabetes and Obesity
Lipidomics in diabetes : Current Opinion in Endocrinology, Diabetes and Obesity Log in or …

The role of transcription factor 7‐like 2 in metabolic disorders

Z Zhang, L Xu, X Xu - Obesity Reviews, 2021 - Wiley Online Library
Summary Transcription factor 7‐like 2 (TCF7L2), a member of the T cell factor/lymphoid
enhancer factor family, generally forms a complex with β‐catenin to regulate the …

Down-regulation of SETD6 protects podocyte against high glucose and palmitic acid-induced apoptosis, and mitochondrial dysfunction via activating Nrf2-Keap1 …

X Wang, Q Liu, D Kong, Z Long, YF Guo… - Journal of Molecular …, 2020 - Springer
Diabetic nephropathy (DN), a serious complication of hyperglycemia, is one of the most
common causes of end-stage renal disease (ESRD). Glomerular podocyte injury is a major …

Optimization of a GC-MS method for the profiling of microbiota-dependent metabolites in blood samples: An application to type 2 diabetes and prediabetes

P Mojsak, K Maliszewska, P Klimaszewska… - Frontiers in Molecular …, 2022 - frontiersin.org
Changes in serum or plasma metabolome may reflect gut microbiota dysbiosis, which is also
known to occur in patients with prediabetes and type 2 diabetes (T2DM). Thus, developing a …

Evaluation of different tandem MS acquisition modes to support metabolite annotation in human plasma using ultra high-performance liquid chromatography high …

J Pezzatti, V González-Ruiz, J Boccard, D Guillarme… - Metabolites, 2020 - mdpi.com
Ultra-high performance liquid chromatography coupled to high-resolution mass
spectrometry (UHPLC-HRMS) is a powerful and essential technique for metabolite …

Chronic kidney disease cohort studies: A guide to metabolome analyses

UT Schultheiss, R Kosch, F Kotsis, M Altenbuchinger… - Metabolites, 2021 - mdpi.com
Kidney diseases still pose one of the biggest challenges for global health, and their
heterogeneity and often high comorbidity load seriously hinders the unraveling of their …

Dietary macronutrient intake may influence the effects of TCF7L2 rs7901695 genetic variants on glucose homeostasis and obesity-related parameters: A cross …

W Bauer, E Adamska-Patruno, U Krasowska, M Moroz… - Nutrients, 2021 - mdpi.com
Transcription factor-7–like 2 (TCF7L2) is one of the most important susceptibility genes for
type 2 diabetes mellitus (T2DM). The aim of our cross-sectional population-based study was …