Nitrated-polycyclic aromatic hydrocarbons (nitro-PAHs) and diesel exhaust particle extracts
(DEPE) induced apoptosis in Hepa1c1c7 cells with the following potency: 1, 3-dinitropyrene …

Stress causes decreased cell accumulation in early periimplantation embryos and the
placental trophoblast stem cells derived from them. Benzopyrene and many other stressors …

Bone loss due to smoking represents a major risk factor for fractures and bone osteoporosis.
Signaling through the aryl hydrocarbon receptor (AhR) and its ligands contributes to both …

Following the development of an experimental system to expose adult fish to low and stable
concentration of pollutant over a prolonged period, the in vivo effects of hydrocarbons on …

The present study compares and elucidates possible mechanisms why B [a] P induces
different cell signals and triggers apparently different apoptotic pathways in two rather …

We have previously shown that acute oral exposure to the environmental carcinogen benzo
(a) pyrene (BaP) elicits comparable levels of DNA adducts, but distinct transcriptomic …

Cyclophosphamide is one of the most often used anticancer drugs. Although DNA
interstrand cross-links are considered responsible for its cytotoxicity, the mechanism of …

Benzo [a] pyrene (B [a] P) is an environmental contaminant mainly studied for its
toxic/carcinogenic effects. For a comprehensive and pathway orientated mechanistic …

Polycyclic aromatic hydrocarbons are ubiquitous environmental pollutants formed during
incomplete combustion of organic material. For example benzo [a] pyrene (B [a] P) is a …

Introduction 3. Carotenoids and lung cancer risk 3.1. Evidence from epidemiological studies
3.2. Evidence from animal studies 3.2. 1. Beta-carotene 3.2. 2. Lycopene 3.2. 3. Beta …