The intestinal epithelial tight junction (TJ) barrier controls the paracellular permeation of
contents from the intestinal lumen into the intestinal tissue and systemic circulation. A …

The release and absorption profile of an oral medication is influenced by the
physicochemical properties of the drug and its formulation, as well as by the anatomy and …

Highly prevalent conditions with multiple and complex underlying etiologies are a challenge
to public health. Undernutrition, for example, affects 20% of children in the developing world …

Background: Obesity and associated metabolic disorders are related to impairments of the
intestinal barrier. Objective: We examined lactulose: mannitol (Lac: Man) permeability in …

The intestinal barrier serves 2 critical functions for the survival of the individual: first, it allows
nutrient absorption and second, it defends the body from dangerous macromolecule …

BACKGROUND & AIMS: Altered intestinal permeability has been shown to be associated
with metabolic alterations in animal models of obesity, but not in humans. The aim of this …

Background Intestinal permeability is thought to be of major relevance for digestive and
nutrition-related diseases, and therefore has been studied in numerous mouse models of …

Today's growing interest in functional foods is due to their positive impacts on human health.
The aim of this study was to evaluate the probiotic properties and prebiotic metabolism of …

Objectives Drug product performance in patients with gastrointestinal (GI) diseases can be
altered compared to healthy subjects due to pathophysiological changes. In this review …

Reliable quantification of bacterial products such as endotoxin is important for the diagnosis
of Gram-negative infection and for the monitoring of its treatment. Further, it is important to …