SLAMF7 as a promising immunotherapeutic target in multiple myeloma treatments
E Chu, J Wu, SS Kang, Y Kang - Current Oncology, 2023 - mdpi.com
Multiple myeloma (MM) is a common hematological malignancy that has fostered several
new therapeutic approaches to combat newly diagnosed or relapsed MM. While the field …
new therapeutic approaches to combat newly diagnosed or relapsed MM. While the field …
SLAM family-mediated crosstalk between tumor and immune cells in the tumor microenvironment: A promising biomarker and a potential therapeutic target for immune …
LB Kwantwi - Clinical and Translational Oncology, 2024 - Springer
Immune cells infiltrating the tumor microenvironment are physiologically important in
controlling cancers. However, emerging studies have shown that cancer cells can evade …
controlling cancers. However, emerging studies have shown that cancer cells can evade …
Genetic insights into carbohydrate sulfotransferase 8 and its impact on the immunotherapy efficacy of cancer
Immune checkpoint blockade (ICB) is a promising therapy for solid tumors, but its
effectiveness depends on biomarkers that are not precise. Here, we utilized genome-wide …
effectiveness depends on biomarkers that are not precise. Here, we utilized genome-wide …
Modulating macrophage-mediated programmed cell removal: An attractive strategy for cancer therapy
Z Li, B Han, M Qi, Y Li, Y Duan, Y Yao - Biochimica et Biophysica Acta (BBA …, 2024 - Elsevier
Macrophage-mediated programmed cell removal (PrCR) is crucial for the identification and
elimination of needless cells that maintain tissue homeostasis. The efficacy of PrCR …
elimination of needless cells that maintain tissue homeostasis. The efficacy of PrCR …
Repolarization of immunosuppressive macrophages by targeting SLAMF7-regulated CCL2 signaling sensitizes hepatocellular carcinoma to immunotherapy
J Weng, Z Wang, Z Hu, W Xu, JL Sun, F Wang, Q Zhou… - Cancer Research, 2024 - AACR
Immune checkpoint inhibitors have limited efficacy in hepatocellular carcinoma (HCC).
Macrophages are the most abundant immune cells in HCC, suggesting that a better …
Macrophages are the most abundant immune cells in HCC, suggesting that a better …
Multifaceted perspectives of detecting and targeting solid tumors
A Bhattacharya, AK Dasgupta - International review of …, 2024 - pubmed.ncbi.nlm.nih.gov
Solid tumors are the most prevalent form of cancer. Considerable technological and medical
advancements had been achieved for the diagnosis of the disease. However, detection of …
advancements had been achieved for the diagnosis of the disease. However, detection of …
Kanser İlişkili Yeni Hedef Molekül SLAMF7
Kanser hücre için kontrolsüz büyüme getirisi sağlayan, geniş bir çeşitlilik ve karmaşık
süreçlerle karakterize edilir. Hastalığın erken teşhisi, prognozun iyileştirilmesi, sağkalım …
süreçlerle karakterize edilir. Hastalığın erken teşhisi, prognozun iyileştirilmesi, sağkalım …
Estudio de la función de SLAMF8 en macrófagos
S Romero Pinedo - 2024 - digibug.ugr.es
En primer lugar, se realizó un estudio sobre la activación de NOX2 a través de vías directas
e indirectas de PKC en Mϕ de ratones deficientes para SLAMF8 (SLAMF8-/-) en …
e indirectas de PKC en Mϕ de ratones deficientes para SLAMF8 (SLAMF8-/-) en …