The progression of inorganic nanoparticles and natural products for inflammatory bowel disease

Q Li, L Lin, C Zhang, H Zhang, Y Ma, H Qian… - Journal of …, 2024 - Springer
There is a growing body of evidence indicating a close association between inflammatory
bowel disease (IBD) and disrupted intestinal homeostasis. Excessive production of reactive …

Organoruthenium-bipyridyl complexes–A platform for diverse chemistry and applications

C Pandya, A Sivaramakrishna - Coordination Chemistry Reviews, 2024 - Elsevier
The increasing impact of organometallic complexes of group 8–10 metals academically and
industrially over the years demonstrates remarkable progress in harvesting useful reagents …

Ruthenium-based metal-organic framework with reactive oxygen and nitrogen species scavenging activities for alleviating inflammation diseases

J Liu, L Shi, Y Wang, M Li, C Zhou, L Zhang, C Yao… - Nano Today, 2022 - Elsevier
The overproduction of reactive oxygen and nitrogen species (RONS) is highly associated
with a variety of inflammatory diseases. Nevertheless, few treatments are clinically available …

Increasing anticancer activity with phosphine ligation in zwitterionic half-sandwich iridium (III), rhodium (III), and ruthenium (II) complexes

X Hu, L Guo, M Liu, Q Zhang, Y Gong, M Sun… - Inorganic …, 2022 - ACS Publications
The synthesis and biological assessment of neutral or cationic platinum group metal-based
anticancer complexes have been extremely studied, whereas there are few reports on the …

Inhibition of amyloid β1–42 peptide aggregation by newly designed cyclometallated palladium complexes

R Saini, GR Navale, S Singh, HK Singh… - International Journal of …, 2023 - Elsevier
Uncontrolled amyloid aggregation is a frequent cause of neurodegenerative disorders such
as prions and Alzheimer's disease (AD). As a result, many drug development approaches …

Design and synthesis of piano-stool ruthenium (II) complexes and their studies on the inhibition of amyloid β (1–42) peptide aggregation

S Singh, GR Navale, S Agrawal, HK Singh… - International journal of …, 2023 - Elsevier
Misfolding and protein aggregation have been linked to numerous human
neurodegenerative disorders such as Alzheimer's, prion, and Parkinson's diseases …

DNA binding, antitubercular, antibacterial and anticancer studies of newly designed piano-stool ruthenium (II) complexes

G Navale, S Singh, S Agrawal, C Ghosh… - Dalton …, 2022 - pubs.rsc.org
The chemotherapeutic potential of ruthenium (II) complexes has recently attracted
researchers' interest as antibacterial and anticancer agents. In this study, two novel half …

Transition Metal Complexes as Therapeutics: A New Frontier in Combatting Neurodegenerative Disorders through Protein Aggregation Modulation

GR Navale, I Ahmed, MH Lim… - Advanced Healthcare …, 2024 - Wiley Online Library
Neurodegenerative disorders (NDDs) are a class of debilitating diseases that progressively
impair the protein structure and result in neurological dysfunction in the nervous system …

Metal complexes as promising matrix metalloproteinases regulators

YT Nguyen, N Kim, HJ Lee - International Journal of Molecular Sciences, 2023 - mdpi.com
Nowadays, cancers and dementia, such as Alzheimer's disease, are the most fatal causes of
death. Many studies tried to understand the pathogenesis of those diseases clearly and …

An overview of the potential medicinal and pharmaceutical properties of Ru (II)/(III) complexes

A Skoczynska, A Lewinski, M Pokora, P Paneth… - International Journal of …, 2023 - mdpi.com
This review examines the existing knowledge about Ru (II)/(III) ion complexes with a
potential application in medicine or pharmacy, which may offer greater potential in cancer …